ArticleJournal of virology1996
Transcriptional activation function is not required for stimulation of DNA replication by bovine papillomavirus type 1 E2.
Article in Journal of virology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 43 citations in OpenAlex.
- Acetylation of E2 by P300 Mediates Topoisomerase Entry at the Papillomavirus Replicon.Journal of virology · 2019Article
- Levels of the E2 interacting protein TopBP1 modulate papillomavirus maintenance stage replication.Virology · 2015Article
- Genetic analysis of the E2 transactivation domain dimerization interface from bovine papillomavirus type 1.Virology · 2013Article
- Acetylation of conserved lysines in bovine papillomavirus E2 by p300.Journal of virology · 2013Article
- Targeting human papillomavirus genome replication for antiviral drug discovery.Antiviral therapy · 2013Review
- Proteasomal degradation of the papillomavirus E2 protein is inhibited by overexpression of bromodomain-containing protein 4.Journal of virology · 2009Article
- Dual roles of an essential cysteine residue in activity of a redox-regulated bacterial transcriptional activator.The Journal of biological chemistry · 2008Article
- Mitotic kinesin-like protein 2 binds and colocalizes with papillomavirus E2 during mitosis.Journal of virology · 2007Article
- Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation function.Journal of virology · 2006Article
- Conditional mutations in the mitotic chromosome binding function of the bovine papillomavirus type 1 E2 protein.Journal of virology · 2005Article
- Analysis of chromatin attachment and partitioning functions of bovine papillomavirus type 1 E2 protein.Journal of virology · 2004Article
- A transactivator function of cottontail rabbit papillomavirus e2 is essential for tumor induction in rabbits.Journal of virology · 2002Article
- Papillomavirus E1 proteins: form, function, and features.Virus genes · 2002Review
- AMF-1/Gps2 binds p300 and enhances its interaction with papillomavirus E2 proteins.Journal of virology · 2000Article
- Mechanisms of human papillomavirus E2-mediated repression of viral oncogene expression and cervical cancer cell growth inhibition.Journal of virology · 2000Article
- Role of the ATP-binding domain of the human papillomavirus type 11 E1 helicase in E2-dependent binding to the origin.Journal of virology · 1999Article
- Effect of bovine papillomavirus E2 protein-specific monoclonal antibodies on papillomavirus DNA replication.Journal of virology · 1999Article
- A fifteen-amino-acid peptide inhibits human papillomavirus E1-E2 interaction and human papillomavirus DNA replication in vitro.Journal of virology · 1998Article
- Transactivation by the E2 protein of oncogenic human papillomavirus type 31 is not essential for early and late viral functions.Journal of virology · 1998Article
- Transactivation-competent bovine papillomavirus E2 protein is specifically required for efficient repression of human papillomavirus oncogene expression and for acute growth inhibition of cervical carcinoma cell lines.Journal of virology · 1998Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Bovine papillomavirus type 1 replication was previously shown to require both the E1 initiator protein and the E2 transactivator protein. We show here that E1, in the absence of E2, is sufficient for low-level bovine papillomavirus type 1 DNA replication in C-33A cells. In addition, studies of genetically isolated E2 point mutants demonstrate that enhancement of replication by E2 does not require its transcriptional activation function. The uncoupling of the E2 functions suggests that stimulation of transcription and replication by enhancer proteins occurs via divergent mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.