ReviewPharmaceutical research1995
Biology of membrane transport proteins.
Review in Pharmaceutical research, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 53 citations in OpenAlex.
- Multiple interactions of cimetidine and probenecid with valaciclovir and its metabolite acyclovir.Antimicrobial agents and chemotherapy · 2002Trial
- Enhanced identification of membrane transport proteins: a hybrid approach combining ProtBERT-BFD and convolutional neural networks.Journal of integrative bioinformatics · 2023Article
- Modulation of antimicrobial efflux pumps of the major facilitator superfamily inAIMS microbiology · 2018Review
- Simulations of the nonlinear dose dependence for substrates of influx and efflux transporters in the human intestine.The AAPS journal · 2009Article
- Pharmacogenomics and systems biology of membrane transporters.Molecular biotechnology · 2005Review
- Monitoring intracellular pH changes in response to osmotic stress and membrane transport activity using 5-chloromethylfluorescein.AAPS pharmSci · 2002Article
- Genomic structure of proton-coupled oligopeptide transporter hPEPT1 and pH-sensing regulatory splice variant.AAPS pharmSci · 2001Article
- Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein.AAPS pharmSci · 2001Article
- Human membrane transporter database: a Web-accessible relational database for drug transport studies and pharmacogenomics.AAPS pharmSci · 2000Article
- Detection of the membrane protein recognized by the kidney-specific alkylglucoside vector.Pharmaceutical research · 2000Article
- 16th SMYTE (Small Meeting on Yeast Transport and Energetics). Casta-Papiernicka, Slovakia, September 23-27, 1998. Abstracts.Folia microbiologica · 1999Article
- Chimeric purine transporters of Aspergillus nidulans define a domain critical for function and specificity conserved in bacterial, plant and metazoan homologues.The EMBO journal · 1998Article
- Sequence alignments of the H(+)-dependent oligopeptide transporter family PTR: inferences on structure and function of the intestinal PET1 transporter.Pharmaceutical research · 1997Article
- Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells.Pharmaceutical research · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Membrane transporter proteins are encoded by numerous genes that can be classified into several superfamilies, on the basis of sequence identity and biological function. Prominent examples include facilitative transporters, the secondary active symporters and antiporters driven by ion gradients, and active ABC (ATP binding cassette) transporters involved in multiple-drug resistance and targeting of antigenic peptides to MHC Class I molecules. Transported substrates range from nutrients and ions to a broad variety of drugs, peptides and proteins. Deleterious mutations of transporter genes may lead to genetic diseases or loss of cell viability. Transporter structure, function and regulation, genetic factors, and pharmaceutical implications are summarized in this review.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.