Evidence map›Paper›PMID 8785281›Full record

ArticleBiophysical journal1996

Anomalous diffusion due to binding: a Monte Carlo study.

M J Saxton

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 1 synthesis or guideline pooled it, 344 citations in OpenAlex.

  1. Pooled it
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  16. High-Precision Protein-Tracking With Interferometric Scattering Microscopy.Frontiers in cell and developmental biology · 2020
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  17. Cadherin Extracellular Domain Clustering in the Absence ofThe journal of physical chemistry letters · 2019
    Article
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

M J SaxtonInstitute of Theoretical Dynamics, University of California, Davis 95616, USA. mjsaxton@ucdavis.edu
University of California, Davis · US

Funding

LATERAL DIFFUSION IN AN ARCHIPELAGO: MONTE CARLO STUDIESR01GM038133 · NIGMS · UNIVERSITY OF CALIFORNIA DAVIS · PI SAXTON, MICHAEL J. · 1988 to 2011
$1.9M
NIGMS NIH HHS GM38133
6 · The paper itself

Abstract

In classical diffusion, the mean-square displacement increases linearly with time. But in the presence of obstacles or binding sites, anomalous diffusion may occur, in which the mean-square displacement is proportional to a nonintegral power of time for some or all times. Anomalous diffusion is discussed for various models of binding, including an obstruction/binding model in which immobile membrane proteins are represented by obstacles that bind diffusing particles in nearest-neighbor sites. The classification of binding models is considered, including the distinction between valley and mountain models and the distinction between singular and nonsingular distributions of binding energies. Anomalous diffusion is sensitive to the initial conditions of the measurement. In valley models, diffusion is anomalous if the diffusing particles start at random positions but normal if the particles start at thermal equilibrium positions. Thermal equilibration leads to normal diffusion, or to diffusion as normal as the obstacles allow.

Indexed as

DiffusionModels, BiologicalMonte Carlo MethodAnimalsBinding SitesBiological Transport, ActiveBiophysical PhenomenaBiophysicsHumansPhotochemistryReceptors, LDLThermodynamicsReceptors, LDL

Identifiers

PMID8785281
PMCPMC1225051
OpenAlexW2046320783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.