Trial reportEuropean journal of applied physiology and occupational physiology1996
The effect of salbutamol on performance in endurance cyclists.
Trial report in European journal of applied physiology and occupational physiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- β₂-Agonists and physical performance: a systematic review and meta-analysis of randomized controlled trials.Sports medicine (Auckland, N.Z.) · 2011Pooled it
- High-dose inhaled terbutaline increases muscle strength and enhances maximal sprint performance in trained men.European journal of applied physiology · 2014Trial
- Trial
- Instant effects of peppermint essential oil on the physiological parameters and exercise performance.Avicenna journal of phytomedicine · 2014Article
- The effects of peppermint on exercise performance.Journal of the International Society of Sports Nutrition · 2013Article
- The rush to adrenaline: drugs in sport acting on the beta-adrenergic system.British journal of pharmacology · 2008Review
- Do inhaled beta(2)-agonists have an ergogenic potential in non-asthmatic competitive athletes?Sports medicine (Auckland, N.Z.) · 2007Review
- Inhaled beta2 agonists and performance in competitive athletes.British journal of sports medicine · 2006Review
- Use of beta2 agonists in sport: are the present criteria right?British journal of sports medicine · 2006Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effect of salbutamol (S) on cycling performance was examined in 15 highly trained non-asthmatic male cyclists. A double-blind, randomized cross-over design was used with S or placebo (P) administered using a metered-dose inhaler and a spacer device 20 min before each testing session. The S dose was 400 micrograms (four puffs), which is twice the normal therapeutic level. Subjects were habituated to all the laboratory procedures in the week prior to actual data collection. The subjects performed four tests under S and P conditions on separate days over 2 weeks. These included measurement of maximal O2 uptake (VO2max) (cycle ergometry) with assessment of pulmonary function before and after, a submaximal (90% of ventilatory threshold) square-wave work transition from a base of unloaded cycling, a 60-s modified Wingate test, and a simulated 20 km time trial. No significant differences were observed in any of the dependent variables related to aerobic endurance or cycling performance between the S and P conditions. These results support other findings that an acute dose (400 micrograms) of S has no performance-enhancing properties.
Indexed as
Identifiers
8781870What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.