ArticlePflugers Archiv : European journal of physiology1996
Dependence of solution exchange time on cell or patch linear dimensions in concentration jump experiments using patch-clamped sensory neurones.
Article in Pflugers Archiv : European journal of physiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Neurophysiology of Nicotine Addiction.Journal of addiction research & therapy · 2011Article
- A chemical waveform synthesizer.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A critical evaluation of "concentration jump" techniques employing hydrodynamic solution exchange has been undertaken. Data obtained from experiments using acutely isolated sensory neurones demonstrated a dependence of the total solution exchange time on the linear dimensions of the preparation. The exchange time around a circular surface is proportional to the radius of this surface. A quantitative approximation can be formulated as follows: if the membrane area of the object under investigation is increased n times, the duration of the full solution exchange is increased by radical n times. A nonlinear dependence of exchange time on vacuum pressure was confirmed in a separate set of experiments.
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Registered trials
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