Activated ras. Yet another player in melanoma?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed.

1. Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth.Cell death and differentiation · 2011
   Article
2. Metastasis in an orthotopic murine model of melanoma is independent of RAS/RAF mutation.Melanoma research · 2010
   Article
3. Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformation.Pigment cell & melanoma research · 2008
   Article
4. Role of nuclear factor-kappa B in melanoma.Cancer metastasis reviews · 2005
   Review
5. Role of epidermal growth factor receptor signaling in RAS-driven melanoma.Molecular and cellular biology · 2005
   Article
6. HGF induces fibronectin matrix synthesis in melanoma cells through MAP kinase-dependent signaling pathway and induction of Egr-1.Oncogene · 2005
   Article
7. Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma.The Journal of investigative dermatology · 2004
   Article
8. Both products of the mouse Ink4a/Arf locus suppress melanoma formation in vivo.Oncogene · 2003
   Article
9. The INK4a/ARF locus and melanoma.Oncogene · 2003
   Review
10. Understanding the progression of melanocytic neoplasia using genomic analysis: from fields to cancer.Oncogene · 2003
    Review
11. Death receptors and melanoma resistance to apoptosis.Oncogene · 2003
    Review
12. Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model.Proceedings of the National Academy of Sciences of the United States of America · 2003
    Article
13. Mutations and copy number increase of HRAS in Spitz nevi with distinctive histopathological features.The American journal of pathology · 2000
    Article
14. Pigmented uveal tumours in a transgenic mouse model.The British journal of ophthalmology · 1998
    Article

Corrections and comments

• Comment on
  Relevance of ultraviolet-induced N-ras oncogene point mutations in development of primary human cutaneous melanoma.1996

Authors and funding

2 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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