ArticleGenetics1996
A genetic map of quantitative trait loci for body weight in the mouse.
Article in Genetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 114 citations in OpenAlex.
- Body size and cranial shape differentiation in urban and rural house mice (bioRxiv : the preprint server for biology · 2026Article
- Gene-by-environment Interactions and Adaptive Body Size Variation in Mice From the Americas.Molecular biology and evolution · 2025Article
- An integrative genomic analysis of the Longshanks selection experiment for longer limbs in mice.eLife · 2019Article
- Mapping novel genetic loci associated with female liver weight variations using Collaborative Cross mice.Animal models and experimental medicine · 2018Article
- Genetics of Rapid and Extreme Size Evolution in Island Mice.Genetics · 2015Article
- Inferring genetic architecture of complex traits using Bayesian integrative analysis of genome and transcriptome data.BMC genomics · 2012Article
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- Genetic loci affecting body weight and fatness in a C57BL/6J x PWK/PhJ mouse intercross.Mammalian genome : official journal of the International Mammalian Genome Society · 2007Article
- Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity.PLoS genetics · 2006Article
- Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci.Mammalian genome : official journal of the International Mammalian Genome Society · 2006Article
- Genetics of body weight in the LXS recombinant inbred mouse strains.Mammalian genome : official journal of the International Mammalian Genome Society · 2005Article
- Theoretical models of selection and mutation on quantitative traits.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2005Review
- Adjusting data to body size: a comparison of methods as applied to quantitative trait loci analysis of musculoskeletal phenotypes.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2005Article
- Quantitative trait loci analysis of structural and material skeletal phenotypes in C57BL/6J and DBA/2 second-generation and recombinant inbred mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2005Article
- Development of a highly fecund inbred strain of mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- QTLs for pre- and postweaning body weight and body composition in selected mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- A large-sample QTL study in mice: I. Growth.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- Two ENU-induced mutations in Rasgrf1 and early mouse growth retardation.Mammalian genome : official journal of the International Mammalian Genome Society · 2003Article
- Loci on chromosomes 2, 4, 9, and 16 for body weight, body length, and adiposity identified in a genome scan of an F2 intercross between the 129P3/J and C57BL/6ByJ mouse strains.Mammalian genome : official journal of the International Mammalian Genome Society · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genetic basis of body weight in the mouse was investigated by measuring frequency changes of microsatellite marker alleles in lines divergently selected for body weight from a base population of a cross between two inbred strains. In several regions of the genome, sharp peaks of frequency change at linked markers were detected, which suggested the presence of single genes of moderate effect, although in several other regions, significant frequency changes occurred over large portions of chromosomes. A method based on maximum likelihood was used to infer effects and map positions of quantitative trait loci (QTLs) based on genotype frequencies at one or more marker loci. Eleven QTLs with effects in the range 0.17-0.28 phenotypic standard deviations were detected; but under an additive model, these did not fully account for the observed selection response. Tests for the presence of more than one QTL in regions where there were large changes of marker allele frequency were mostly inconclusive.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.