Evidence map›Paper›PMID 8764959›Full record

ArticlePflugers Archiv : European journal of physiology1996

Potassium channels of adult locust (Schistocerca gregaria) muscle.

E Gorczynska, P L Huddie, B A Miller, I R Mellor, H Vais, R L Ramsey, P N Usherwood

Abstract read
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In one paragraph

Article in Pflugers Archiv : European journal of physiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

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  4. Potassium channels of adult locust (Schistocerca gregaria) muscle.Pflugers Archiv : European journal of physiology · 1996
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

E GorczynskaDepartment of Life Science, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
P L Huddie
B A Miller
I R Mellor
H Vais
R L Ramsey
P N Usherwood
University of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two types of K+ channels have been identified in patches of plasma membrane of metathoracic extensor tibiae muscle fibres of adult locust, Schistocerca gregaria. One channel had a maximum conductance of 170 pS, fast open-closed kinetics, and a linear current/ voltage relationship. In inside-out patches it was activated by "internally applied" Ca2+, but at unexpectedly low levels (between 10(-10) and 10(-9)M). The other channel had a maximum conductance of 35 pS, slower open-closed kinetics, and was not activated by Ca2+. In cell-attached patches, its channel conductance measured in symmetrical salines was about three times greater for hyperpolarisations than for depolarisations. This inward rectification was proved to be due to block by intracellular Mg2+. For both channels, open probability (Po) and mean open time increased during depolarisations and decreased during hyperpolarisations, resulting in outward rectifications in terms of net current (I n, product of the single-channel current and Po). For both channels, the K+ conductance was 10 times greater than that for Na+. Internally applied tetraethylammonium or tetramethylammonium ions blocked both channels.

Indexed as

Potassium Channels, Calcium-ActivatedAnimalsCalciumCesiumGrasshoppersKineticsLarge-Conductance Calcium-Activated Potassium ChannelsMagnesiumMembrane PotentialsMuscle, SkeletalPotassiumPotassium ChannelsQuaternary Ammonium CompoundsSodiumTetraethylammoniumTetraethylammonium CompoundsCalciumCesiumLarge-Conductance Calcium-Activated Potassium ChannelsMagnesiumPotassiumPotassium ChannelsPotassium Channels, Calcium-ActivatedQuaternary Ammonium CompoundsSodiumTetraethylammoniumTetraethylammonium Compoundstetramethylammonium

Identifiers

PMID8764959
OpenAlexW2071162287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.