Evidence map›Paper›PMID 8763994›Full record

ArticleJournal of virology1996

AP1 enhances polyomavirus DNA replication by promoting T-antigen-mediated unwinding of DNA.

W Guo, W J Tang, X Bu, V Bermudez, M Martin, W R Folk

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Human DNA Virus Exploitation of the MAPK-ERK Cascade.International journal of molecular sciences · 2019
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Natural biology of polyomavirus middle T antigen.Microbiology and molecular biology reviews : MMBR · 2001
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

W GuoDepartment of Biochemistry, University of Missouri--Columbia 65202, USA.
W J Tang
X Bu
V Bermudez
M Martin
W R Folk
University of Missouri · US

Funding

SUPPLEMENT FOR UNDERGRADUATE MINORITIESR01CA038538 · NCI · UNIVERSITY OF TEXAS AUSTIN · PI FOLK, WILLIAM ROBERT · 1985 to 1996
–
NCI NIH HHS CA38538
6 · The paper itself

Abstract

An early step in the initiation of polyomavirus DNA replication is viral large-T-antigen-mediated unwinding of the origin. We report that components of the AP1 transcription factor, Fos and Jun, interact with T antigen in vitro to enhance unwinding of the viral origin. This provides a biochemical basis for the capacity of AP1 to activate viral DNA replication in vivo.

Indexed as

PeroxidasesAntigens, Viral, TumorDNA ReplicationDNA, ViralOncogene Proteins v-fosPeroxiredoxinsPolyomavirusProto-Oncogene Proteins c-junTranscription FactorsVirus ReplicationAntigens, Viral, TumorDNA, ViralOncogene Proteins v-fosPeroxidasesPeroxiredoxinsProto-Oncogene Proteins c-junTranscription Factors

Identifiers

PMID8763994
PMCPMC190441
OpenAlexW1583894442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.