ReviewJournal of bacteriology1996
Fancy meeting you here! A fresh look at "prokaryotic" protein phosphorylation.
Review in Journal of bacteriology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed.
- Molecular mechanisms and consequences of TDP-43 phosphorylation in neurodegeneration.Molecular neurodegeneration · 2025Review
- Functional Prediction of Biological Profile During Eutrophication in Marine Environment.Bioinformatics and biology insights · 2022Article
- Intracellular Ser/Thr/Tyr phosphoproteome of the oral commensal Streptococcus gordonii DL1.BMC microbiology · 2020Article
- Metabolic Kinases Moonlighting as Protein Kinases.Trends in biochemical sciences · 2018Review
- Post-Translational Modifications of Cardiac Mitochondrial Proteins in Cardiovascular Disease: Not Lost in Translation.Korean circulation journal · 2016Review
- Regulation of Escherichia coli RNase III activity.Journal of microbiology (Seoul, Korea) · 2015Review
- Nucleoside diphosphate kinase as protein histidine kinase.Naunyn-Schmiedeberg's archives of pharmacology · 2015Review
- Protein Ser/Thr/Tyr phosphorylation in the Archaea.The Journal of biological chemistry · 2014Review
- Bacterial cell division regulation by Ser/Thr kinases: a structural perspective.Current protein & peptide science · 2012Review
- Contribution of rpoS and bolA genes in biofilm formation in Escherichia coli K-12 MG1655.Molecular and cellular biochemistry · 2010Review
- Article
- Forkhead-associated domain-containing protein Rv0019c and polyketide-associated protein PapA5, from substrates of serine/threonine protein kinase PknB to interacting proteins of Mycobacterium tuberculosis.The Journal of biological chemistry · 2009Article
- Identification of serine/threonine kinase substrates in the human pathogen group B streptococcus.Journal of proteome research · 2009Article
- A PPM-family protein phosphatase from the thermoacidophile Thermoplasma volcanium hydrolyzes protein-bound phosphotyrosine.Extremophiles : life under extreme conditions · 2009Article
- The application of FAST-NMR for the identification of novel drug discovery targets.Drug discovery today · 2008Review
- Genome-wide survey of putative serine/threonine protein kinases in cyanobacteria.BMC genomics · 2007Article
- Identification of sensory and signal-transducing domains in two-component signaling systems.Methods in enzymology · 2007Review
- FAST-NMR: functional annotation screening technology using NMR spectroscopy.Journal of the American Chemical Society · 2006Article
- A eukaryotic-type serine/threonine protein kinase is required for biofilm formation, genetic competence, and acid resistance in Streptococcus mutans.Journal of bacteriology · 2006Article
- A phosphoprotein from the archaeon Sulfolobus solfataricus with protein-serine/threonine kinase activity.Journal of bacteriology · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteria play host to a wide range of protein phosphorylation-dephosphorylation systems (Fig. 1). As little as five years ago the known systems were thought to be late-emerging and absolutely prokaryote specific. Today we know that most protein kinases and protein phosphatases are descended from a set of common, and possibly quite ancient, prototypes. Prokaryote- and eukaryote-specific protein kinases and protein phosphatases are rare and represent exceptions, not the rule as previously thought. Commonality suggests that a dynamic and versatile regulatory mechanism was first adapted to the modulation of protein function as early if not earlier than more "basic" mechanisms such as allosterism, etc. The existence of common molecular themes confirms that the microbial world offers a unique, largely untapped library and a powerful set of tools for the understanding of a regulatory mechanism which is crucial to all organisms, tools whose diversity and experimental malleability will provide new avenues for exploring and understanding key modes of cellular regulation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.