ArticleInfection and immunity1996
Cloning, sequencing, expression, and protective capacity of the oma87 gene encoding the Pasteurella multocida 87-kilodalton outer membrane antigen.
Article in Infection and immunity, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 71 citations in OpenAlex.
- Developing a PmSLP3-based vaccine formulation that provides robust long-lasting protection against hemorrhagic septicemia-causing serogroup B and E strains ofFrontiers in immunology · 2024Article
- In-silico identification of linear B-cell epitopes in specific proteins of Bartonella bacilliformis for the serological diagnosis of Carrion's disease.PLoS neglected tropical diseases · 2023Article
- OMPdb: A Global Hub of Beta-Barrel Outer Membrane Proteins.Frontiers in bioinformatics · 2021Article
- Overview ofIndian journal of microbiology · 2020Review
- Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology.Frontiers in immunology · 2017Article
- A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326.Journal of bacteriology · 2015Article
- Pasteurella multocida: from zoonosis to cellular microbiology.Clinical microbiology reviews · 2013Review
- Cloning, sequencing and in silico analysis of omp C of salmonella typhimurium.ISRN veterinary science · 2012Article
- Immunogenicity of Mannheimia haemolytica recombinant outer membrane proteins serotype 1-specific antigen, OmpA, OmpP2, and OmpD15.Clinical and vaccine immunology : CVI · 2011Article
- Outer membrane proteome of Burkholderia pseudomallei and Burkholderia mallei from diverse growth conditions.Journal of proteome research · 2011Article
- Conserved properties of polypeptide transport-associated (POTRA) domains derived from cyanobacterial Omp85.The Journal of biological chemistry · 2010Article
- Filling the gap, evolutionarily conserved Omp85 in plastids of chromalveolates.The Journal of biological chemistry · 2010Article
- Microarray-based comparative genomic profiling of reference strains and selected Canadian field isolates of Actinobacillus pleuropneumoniae.BMC genomics · 2009Article
- Cloning, overexpression, purification, and immunobiology of an 85-kilodalton outer membrane protein from Haemophilus ducreyi.Infection and immunity · 2001Article
- Leptospiral outer membrane proteins OmpL1 and LipL41 exhibit synergistic immunoprotection.Infection and immunity · 1999Article
- The evolutionary origin of the protein-translocating channel of chloroplastic envelope membranes: identification of a cyanobacterial homolog.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Origin of a chloroplast protein importer.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Physical and genetic map of the Pasteurella multocida A:1 chromosome.Journal of bacteriology · 1998Article
- Role of outer membrane protein H (OmpH)- and OmpA-specific monoclonal antibodies from hybridoma tumors in protection of mice against Pasteurella multocida.Infection and immunity · 1997Article
- Identification, purification, and characterization of the type 4 fimbriae of Pasteurella multocida.Infection and immunity · 1997Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Membrane proteins of Pasteurella multocida have been shown previously to elicit protective immunity. We have identified an 87-kDa outer membrane antigen, Oma87, which is present in all 16 serotypes of P. multocida. The gene encoding this protein was cloned and sequenced and found to have significant similarity to the D15 protective surface antigen of Haemophilus influenzae. Oma87 was localized to the outer membrane of the cell, and proteinase K treatment suggested that the protein is surface exposed. Native and recombinant Oma87 were strongly immunostained by convalescent-phase antiserum, indicating that the protein is expressed in vivo. Specific Oma87 antiserum protected mice against homologous, lethal P. multocida challenge. These results suggest that Oma87 is a protective outer membrane antigen of P. multocida.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.