ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1996
Myomodulin gene of Lymnaea: structure, expression, and analysis of neuropeptides.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 39 citations in OpenAlex.
- Oviducal gland transcriptomics ofPeerJ · 2022Article
- Development and Interrogation of a Transcriptomic Resource for the Giant Triton Snail (Charonia tritonis).Marine biotechnology (New York, N.Y.) · 2021Article
- Neuropeptide Localization inFrontiers in molecular neuroscience · 2021Review
- Identification and functional characterization of the first molluscan neuromedin U receptor in the slug, Deroceras reticulatum.Scientific reports · 2020Article
- The unlimited potential of the great pond snail,eLife · 2020Article
- Exploring the Fundamental Structures of Life: Non-Targeted, Chemical Analysis of Single Cells and Subcellular Structures.Angewandte Chemie (International ed. in English) · 2019Review
- Multifaceted Expression of Peptidergic Modulation in the Feeding System of Aplysia.ACS chemical neuroscience · 2018Review
- Identification and Characterization of Neuropeptides by Transcriptome and Proteome Analyses in a Bivalve MolluscFrontiers in genetics · 2018Article
- Marked changes in neuropeptide expression accompany broadcast spawnings in the gastropod Haliotis asinina.Frontiers in zoology · 2012Article
- Different phases of long-term memory require distinct temporal patterns of PKA activity after single-trial classical conditioning.Learning & memory (Cold Spring Harbor, N.Y.) · 2008Article
- Endocrine disruption in aquatic pulmonate molluscs: few evidences, many challenges.Ecotoxicology (London, England) · 2007Review
- Functional implications of neurotransmitter expression during axonal regeneration: serotonin, but not peptides, auto-regulate axon growth of an identified central neuron.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- Neuronal expression of an FMRFamide-gated Na+ channel and its modulation by acid pH.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- Peptide cotransmitter release from motorneuron B16 in aplysia californica: costorage, corelease, and functional implications.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
- Functional redundancy of FMRFamide-related peptides at the Drosophila larval neuromuscular junction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1998Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The myomodulin family of neuropeptides is an important group of neural cotransmitters in molluscs and is known to be present in the neural network that controls feeding behavior in the snail Lymnaea. Here we show that a single gene encodes five structurally similar forms of myomodulin: GLQMLRLamide, QIPMLRLamide, SMSMLRLamide, SLSMLRLamide, and PMSMLRLamide, the latter being present in nine copies. Analysis of the organization of the gene indicates that it is transcribed as a single spliced transcript from an upstream promoter region that contains multiple cAMP-responsive elements, as well as putative elements with homology to tissue-specific promoter-binding sites. The presence in nervous tissue of two of the peptides, GLQMLRLamide and PMSMLRLamide, is confirmed by mass spectrometry. In situ hybridization analysis indicates that the gene is expressed in specific cells in all ganglia of the CNS of Lymnaea, which will allow physiological analysis of the function of myomodulins at the level of single identified neurons.
Indexed as
Identifiers
8756426PMC6579316W2162977105What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.