ArticleProceedings of the National Academy of Sciences of the United States of America1996
Starburst amacrine cells change from spiking to nonspiking neurons during retinal development.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- The Interplay between Neurotransmitters and Calcium Dynamics in Retinal Synapses during Development, Health, and Disease.International journal of molecular sciences · 2024Review
- Modeling cholinergic retinal waves: starburst amacrine cells shape wave generation, propagation, and direction bias.Scientific reports · 2023Article
- Colour and melanopsin mediated responses in the murine retina.Frontiers in cellular neuroscience · 2023Article
- Nonspiking Interneurons in theeNeuro · 2023Article
- Activation of oxytocin receptors in mouse GABAergic amacrine cells modulates retinal dopaminergic signaling.BMC biology · 2022Article
- Article
- Melanopsin Driven Light Responses Across a Large Fraction of Retinal Ganglion Cells in a Dystrophic Retina.Frontiers in neuroscience · 2020Article
- Voltage- and calcium-gated ion channels of neurons in the vertebrate retina.Progress in retinal and eye research · 2019Review
- A biophysical model explains the spontaneous bursting behavior in the developing retina.Scientific reports · 2019Article
- Designing tools for assumption-proof brain mapping.Neuron · 2014Review
- Assembly and disassembly of a retinal cholinergic network.Visual neuroscience · 2012Review
- Organization and development of direction-selective circuits in the retina.Trends in neurosciences · 2011Review
- The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Direction-selective circuitry in rat retina develops independently of GABAergic, cholinergic and action potential activity.PloS one · 2011Article
- Tetrodotoxin-resistant sodium channels contribute to directional responses in starburst amacrine cells.PloS one · 2010Article
- Synaptic regulation of the light-dependent oscillatory currents in starburst amacrine cells of the mouse retina.Journal of neurophysiology · 2008Article
- Disruption and recovery of patterned retinal activity in the absence of acetylcholine.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- A unique role for Kv3 voltage-gated potassium channels in starburst amacrine cell signaling in mouse retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2004Article
- Spontaneous activity in developing turtle retinal ganglion cells: pharmacological studies.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1999Article
- Retinal waves are governed by collective network properties.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1999Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The membrane excitability of cholinergic (starburst) amacrine cells was studied in the rabbit retina during postnatal development. Whole-cell patch-clamp recordings were made from 110 displaced starburst cells in a thin retina] slice preparation of rabbits between postnatal days P1 and P56 old. We report that displaced starburst cells undergo a dramatic transition from spiking to nonspiking, caused by a loss of voltage-gated Na currents. This change in membrane excitability occurred just after eye opening (P10), such that all of the starburst cells tested before eye opening had conspicuous tetrodotoxin-sensitive Na currents and action potentials, but none tested after the first 3 postnatal weeks had detectable Na currents or spikes. Our results suggest that starburst cells use action potentials transiently during development and probably play a functional role in visual development. These cells then cease to spike as the retina matures, presumably consistent with their role in visual processing in the mature retina.
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