Evidence map›Paper›PMID 8751948›Full record

ArticleInfection and immunity1996

Influence of anti-Actinobacillus actinomycetemcomitans Y4 (serotype b) lipopolysaccharide on severity of generalized early-onset periodontitis.

J V Califano, J C Gunsolley, K Nakashima, H A Schenkein, M E Wilson, J G Tew

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 42 citations in OpenAlex.

  1. Peptidoglycan-associated lipoprotein ofJournal of oral microbiology · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J V CalifanoMedical College of Virginia/Virginia Commonwealth University, Richmond 23298-0566, USA.
J C Gunsolley
K Nakashima
H A Schenkein
M E Wilson
J G Tew
Virginia Commonwealth University Medical Center · US

Funding

RESEARCH CENTER FOR PERIODONTAL DISEASESP50DE010703 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI SCHENKEIN, HARVEY ALLEN · 1993 to 1998
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IGG SUBCLASS RESPONSE TO A ACTINOMYCETEMCOMITANSR01DE010041 · NIDCR · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI WILSON, MARK E · 1992 to 1998
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PROTECTIVE ANTIBODY RESPONSES IN JUVENILE PERIODONTITISR29DE010371 · NIDCR · VIRGINIA COMMONWEALTH UNIVERSITY · PI CALIFANO, JOSEPH V. · 1992 to 1996
–
NIDCR NIH HHS DE10041NIDCR NIH HHS DE10371NIDCR NIH HHS DE10703
6 · The paper itself

Abstract

The objective of this study was to determine if a relationship exists between antibody reactive with the Actinobacillus actinomycetemcomitans serotype b lipopolysaccharide (LPS) and severity of periodontal disease in generalized early-onset periodontitis (G-EOP). The concentration of antibody reactive with A. actinomycetemcomitans serotype b LPS was determined for 102 G-EOP subjects. Analysis of the relationship between antibody reactive with A. actinomycetemcomitans serotype b LPS and measures of periodontal attachment loss indicated that the patients with the highest concentrations of antibody reactive with A. actinomycetemcomitans serotype b LPS had significantly less attachment loss. These high-responder subjects also had anti-A. actinomycetemcomitans serotype b LPS with significantly higher relative avidity. The results suggest that antibody reactive with A. actinomycetemcomitans serotype b LPS is protective in G-EOP patients.

Indexed as

AdultAggregatibacter actinomycetemcomitansAntibodies, BacterialAntigens, BacterialFemaleHumansImmunoglobulin GLipopolysaccharidesMalePeriodontitisAntibodies, BacterialAntigens, BacterialImmunoglobulin GLipopolysaccharides

Identifiers

PMID8751948
PMCPMC174312
OpenAlexW2139540956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.