ArticleJournal of muscle research and cell motility1995
Comparison of the foetal development of muscle in normal and double-muscled cattle.
Article in Journal of muscle research and cell motility, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Differential protein input in the maternal diet alters the skeletal muscle transcriptome in fetal sheep.Mammalian genome : official journal of the International Mammalian Genome Society · 2020Article
- Double Muscling in Cattle: Genes, Husbandry, Carcasses and Meat.Animals : an open access journal from MDPI · 2012Review
- Age-related changes and location of types I, III, XII and XIV collagen during development of skeletal muscles from genetically different animals.The Histochemical journal · 2000Article
- Genetic variability of foetal bovine myoblasts in primary culture.The Histochemical journal · 1999Article
- Age-related changes and location of type I, III and IV collagens during skeletal muscle development of double-muscled and normal bovine foetuses.Journal of muscle research and cell motility · 1998Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Muscle differentiation was studied in foetal Semitendinosus muscle from normal cattle and those with the 'culard' gene of muscular hypertrophy sampled at 90, 130, 170 and 210 days of foetal life. The different fibre types were characterized by immunohistochemistry with antibodies specific to different isoforms of myosin heavy chains. The isoforms were separated by electrophoresis, identified by immunoblotting and quantified by ELISA. In double-muscled animals, there was a slower rate of differentiation in the first generation of cells, most markedly apparent at 90 days. At 130 days, differentiation was retarded mainly in the second generation, while at 170 days there was no longer any difference between the two animal types in the differentiation of first generation cells, which were totally slow in both. At the same stage however, type IIC fibres in double-muscled animals were much slower in appearing and continued to be so at 210 days, albeit to a lesser extent. These findings show that differentiation of the muscle fibres occurs at a slower rate in double-muscled foetuses particularly during the first two-thirds of foetal life.
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Registered trials
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