Evidence map›Paper›PMID 8748157›Full record

ArticleGlycoconjugate journal1995

A transgenic mouse line with alpha-1,3/4-fucosyl-transferase cDNA: production and characteristics.

H Obama, T Kaname, A Sudou, T Yanagida, S Ikematsu, M Ozawa, H Yoshida, R Kannagi, K I Yamamura, T Muramatsu

Abstract read
PubMed Publisher
In one paragraph

Article in Glycoconjugate journal, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

H ObamaDepartment of Biochemistry, Kagoshima University, Japan.
T Kaname
A Sudou
T Yanagida
S Ikematsu
M Ozawa
H Yoshida
R Kannagi
K I Yamamura
T Muramatsu
Kagoshima University · JPKumamoto University · JPAichi Cancer Center · JPNagoya University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

cDNA of human alpha-1,3/4-fucosyltransferase (Fuc-TIII) was placed under the control of the chicken beta-actin promoter and cytomegalovirus enhancer, then introduced into male pronuclei of fertilized mouse eggs. A transgenic mouse line thus obtained exhibited enhanced expression of Lex (4C9) antigen in endothelial cells located in the glomerulus, sinusoidal capillaries of the liver and capillaries of the heart. Furthermore, in the transgenic mice, sialyl dimeric Lex (FH6) and sialyl Lea (2D3) antigens were strongly expressed in the glomerular endothelial cells.

Indexed as

AnimalsBase SequenceCarbohydrate ConformationDNA, ComplementaryFucosyltransferasesKidneyLewis X AntigenLiverLungMiceMice, TransgenicMolecular Sequence DataMyocardium3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferaseDNA, ComplementaryFucosyltransferasesLewis X Antigen

Identifiers

PMID8748157
OpenAlexW2031661530

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.