ArticleGlycoconjugate journal1996
Recognition of the blood group H type 2 trisaccharide epitope by 28 monoclonal antibodies and three lectins.
Article in Glycoconjugate journal, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 37 citations in OpenAlex.
- Blood group O expression in normal tissues and tumors.The FEBS journal · 2025Article
- Altered glycosylation of glycodelin in endometrial carcinoma.Laboratory investigation; a journal of technical methods and pathology · 2020Article
- Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Inhibition of the interaction between the SARS-CoV spike protein and its cellular receptor by anti-histo-blood group antibodies.Glycobiology · 2008Article
- Blood group related antigens in ocular cicatricial pemphigoid.The British journal of ophthalmology · 2004Article
- Expression of H type 1 antigen of ABO histo-blood group in normal colon and aberrant expressions of H type 2 and H type 3/4 antigens in colon cancer.Glycoconjugate journal · 2000Article
- Phase variation in Helicobacter pylori lipopolysaccharide due to changes in the lengths of poly(C) tracts in alpha3-fucosyltransferase genes.Infection and immunity · 1999Article
- Interaction of cholera toxin and Escherichia coli heat-labile enterotoxin with glycoconjugates from rabbit intestinal brush border membranes: relationship with ABH blood group determinants.Molecular and cellular biochemistry · 1999Article
- Molecular basis for erythrocyte Le(a+ b+) and salivary ABH partial-secretor phenotypes: expression of a FUT2 secretor allele with an A-->T mutation at nucleotide 385 correlates with reduced alpha(1,2) fucosyltransferase activity.Glycoconjugate journal · 1996Article
- Characterization of the binding specificity of Anguilla anguilla agglutinin (AAA) in comparison to Ulex europaeus agglutinin I (UEA-I).Glycoconjugate journal · 1996Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The patterns of cross-reaction of 30 monoclonal antibodies and three lectins were determined by ELISA with 21 ABH, Ii or Lewis related synthetic oligosaccharides coupled to bovine serum albumin. At least seven main groups of cross-reactive patterns were identified among the antibodies, plus several isolated antibodies which had intermediate patterns between two of the main antibody groups. The three lectins had different cross-reaction patterns, Galactia tenuiflora was different from all the antibodies, Ulex europaeus lectin 1 and Lotus tetragonolobus were similar, but not identical to groups III and V of antibodies respectively. The anti-H antibodies cross-reacting with A type 2 gave similar agglutination scores with all the normal ABO erythrocytes, while the anti-H antibodies not cross-reacting with A type 2 reacted with different scores: O > A2 > A2B > B > A1 > A1B > O(h), suggesting that these antibodies react better with the free H epitopes and do not recognize the H in A or B epitopes. Based on the ELISA and agglutination results and the lowest energy conformations of each oligosaccharide obtained by computer modelling, the most probable oligosaccharide surface areas recognized by each antibody main group are illustrated.
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