ArticleThe Journal of physiology1996
Contribution of a non-inactivating potassium current to the resting membrane potential of fusion-competent human myoblasts.
Article in The Journal of physiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Neuromuscular electrical stimulation training induces myonuclear accretion and hypertrophy in mice without overt signs of muscle damage and regeneration.Skeletal muscle · 2025Article
- A Pharmacological Investigation of the TMEM16A Currents in Murine Skeletal Myogenic Precursor Cells.International journal of molecular sciences · 2024Article
- Ion Channels and Transporters in Muscle Cell Differentiation.International journal of molecular sciences · 2021Review
- Article
- Size and ionic currents of unexcitable cells coupled to cardiomyocytes distinctly modulate cardiac action potential shape and pacemaking activity in micropatterned cell pairs.Circulation. Arrhythmia and electrophysiology · 2012Article
- Role of membrane potential in the regulation of cell proliferation and differentiation.Stem cell reviews and reports · 2009Review
- Three types of single voltage-dependent potassium channels in the sarcolemma of frog skeletal muscle.The Journal of membrane biology · 2009Article
- Potassium currents in human myogenic cells from healthy and congenital myotonic dystrophy foetuses.Cellular & molecular biology letters · 2009Article
- Human myoblast fusion requires expression of functional inward rectifier Kir2.1 channels.The Journal of cell biology · 2001Article
- A new role for ion channels in myoblast fusion.The Journal of cell biology · 2001Review
- T-type alpha 1H Ca2+ channels are involved in Ca2+ signaling during terminal differentiation (fusion) of human myoblasts.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- Mibefradil (Ro 40-5967) inhibits several Ca2+ and K+ currents in human fusion-competent myoblasts.British journal of pharmacology · 1999Article
- An ether -à-go-go K+ current, Ih-eag, contributes to the hyperpolarization of human fusion-competent myoblasts.The Journal of physiology · 1998Article
- Role of an inward rectifier K+ current and of hyperpolarization in human myoblast fusion.The Journal of physiology · 1998Article
- Membrane properties and synaptic inputs of suprachiasmatic nucleus neurons in rat brain slices.The Journal of physiology · 1997Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. Using the patch-clamp technique, a new non-inactivating voltage-gated potassium current, IK(ni), was studied in cultured fusion-competent human myoblasts. 2. IK(ni) is activated at voltages above -50 mV and its conductance reaches its maximum around +50 mV. Once activated, the current remains at a steady level for minutes. 3. Reversal potential measurements at various extracellular potassium concentrations indicate that potassium ions are the major charge carriers of IK(ni). 4. IK(ni) is insensitive to potassium channel blockers such as charybdotoxin, dendrotoxins, mast cell degranulating (MCD) peptide, 4-aminopyridine (4-AP), 3,4-diaminopyridine (3,4-DAP) and apamin, but can be blocked by high concentrations of TEA and by Ba2+. 5. A potassium channel of small conductance (8.4 pS at +40 mV) with potential dependence and pharmacological properties corresponding to those of IK(ni) in whole-cell recording is described. 6. IK(ni) participates in the control of the resting potential of fusion-competent myoblasts, suggesting that it may play a key role in the process of myoblast fusion.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.