ArticleJournal of clinical microbiology1996
Typing Candida albicans oral isolates from human immunodeficiency virus-infected patients by multilocus enzyme electrophoresis and DNA fingerprinting.
Article in Journal of clinical microbiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- Experimental Evolution of PathogenicMicroorganisms · 2026Review
- Evaluating the Typing Power of Six Isoenzymatic Systems for Differentiation of Clinical and Standard Isolates of Candida Species.Advanced biomedical research · 2023Article
- Parasexuality ofFrontiers in cellular and infection microbiology · 2021Review
- Typing Candida albicans oral isolates from healthy brazilian schoolchildren using multilocus enzyme electrophoresis reveals two highly polymorphic taxa.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2011Article
- Article
- Genetic dissection of azole resistance mechanisms in Candida albicans and their validation in a mouse model of disseminated infection.Antimicrobial agents and chemotherapy · 2010Article
- Mating is rare within as well as between clades of the human pathogen Candida albicans.Fungal genetics and biology : FG & B · 2008Article
- Genetic relatedness of commensal strains of Candida albicans carried in the oral cavity of patients' dental prosthesis users in Brazil.Mycopathologia · 2007Article
- Candida albicans strain maintenance, replacement, and microvariation demonstrated by multilocus sequence typing.Journal of clinical microbiology · 2006Article
- Clonal population structure and genetic diversity of Candida albicans in AIDS patients from Abidjan (Côte d'Ivoire).Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Comparison of PCR- and HinfI restriction endonuclease-based methods for typing of Candida krusei isolates.Journal of clinical microbiology · 2004Article
- Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transporters.Antimicrobial agents and chemotherapy · 2004Article
- Genetic diversity among clinical isolates of Candida glabrata analyzed by randomly amplified polymorphic DNA and multilocus enzyme electrophoresis analyses.Journal of clinical microbiology · 2003Article
- Genotyping of Candida albicans oral strains from healthy individuals by polymorphic microsatellite locus analysis.Journal of clinical microbiology · 2003Article
- Genetic structure of Candida glabrata populations in AIDS and non-AIDS patients.Journal of clinical microbiology · 2002Article
- Comparative genotyping of Candida albicans bloodstream and nonbloodstream isolates at a polymorphic microsatellite locus.Journal of clinical microbiology · 2000Article
- The ins and outs of DNA fingerprinting the infectious fungi.Clinical microbiology reviews · 2000Review
- Clonal and spontaneous origins of fluconazole resistance in Candida albicans.Journal of clinical microbiology · 2000Article
- The evolutionary biology and population genetics underlying fungal strain typing.Clinical microbiology reviews · 1999Review
- Candida glabrata: review of epidemiology, pathogenesis, and clinical disease with comparison to C. albicans.Clinical microbiology reviews · 1999Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A total of 189 Candida albicans isolates have been typed by multilocus enzyme electrophoresis. The results obtained confirm the clonal mode of reproduction of C. albicans. The C. albicans populations found in the oropharynx of human immunodeficiency virus (HIV)-infected patients, in the oropharynx of healthy carriers, or in association with invasive candidiasis could not be distinguished. No clone or group of clones could be associated with the appearance of clinical disorders or with a reduced in vitro susceptibility to the antifungal agent fluconazole. Multiple and sequential oral isolates from 24 HIV-infected patients were also typed by restriction enzyme analysis with the enzymes EcoRI and HinfI and by use of the Ca3 repetitive probe. The results obtained by the combination of all three typing methods show that all but one patient each carried a unique major C. albicans clone in their oropharynx. The 21 patients with sequential isolates had the same C. albicans clones in their throats during recurrent oropharyngeal candidiasis episodes, independently of clinical status or of changes of in vitro susceptibility to fluconazole. Finally, several isolates of the same C. albicans clone found simultaneously in the oropharynx of a patient may present different levels of susceptibility to fluconazole.
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