Evidence map›Paper›PMID 8727898›Full record

ArticleJournal of clinical microbiology1996

Novel BOX repeat PCR assay for high-resolution typing of Streptococcus pneumoniae strains.

A van Belkum, M Sluijuter, R de Groot, H Verbrugh, P W Hermans

Abstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Frontiers in microbiology · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A van BelkumDepartment of Clinical Microbiology, University Hospital Rotterdam, Erasmus University, The Netherlands. vanbelkum@bacl.azr.nl
M Sluijuter
R de Groot
H Verbrugh
P W Hermans

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Typing data obtained by specifically targeting a single, high-stringency PCR at the pneumococcal BOX repeat element for 28 strains of Streptococcus pneumoniae completely corroborated the resolutions attained by five genotypic procedures as described by Hermans et al. (P.W.M. Hermans, M. Sluijter, T. Hoogenboezem, H. Heersma, A. van Belkum, and R. de Groot, J. Clin. Microbiol. 33:1606-1612, 1995). All pairs of strains, except one, derived from both the cerebrospinal fluid and blood of the same individual were shown to be identical. Moreover, other, epidemiologically unrelated isolates were demonstrated to be unique. Considering the combined data from the five typing techniques applied previously as the "gold standard," the single BOX PCR test demonstrated excellent resolving powers while maintaining epidemiological linkage.

Indexed as

Bacterial Typing TechniquesRepetitive Sequences, Nucleic AcidBase SequenceDNA, BacterialDNA FingerprintingDNA PrimersHumansMolecular Sequence DataPhylogenyPolymerase Chain ReactionStreptococcus pneumoniaeDNA, BacterialDNA Primers

Identifiers

PMID8727898
PMCPMC228977

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.