Trial reportThorax1996
Prevalence and treatment of chronic airways obstruction in adults over the age of 45.
Trial report in Thorax, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 140 citations in OpenAlex.
- Global and regional estimates of COPD prevalence: Systematic review and meta-analysis.Journal of global health · 2015Pooled it
- Systematic review with meta-analysis of the epidemiological evidence relating smoking to COPD, chronic bronchitis and emphysema.BMC pulmonary medicine · 2011Pooled it
- Variability of the chronic obstructive pulmonary disease key epidemiological data in Europe: systematic review.BMC medicine · 2011Pooled it
- Trial
- Trial
- Effects of glaucoma medications on the cardiorespiratory and intraocular pressure status of newly diagnosed glaucoma patients.The British journal of ophthalmology · 2000Trial
- Randomised, controlled trial of spirometric changes in elderly people receiving timolol or betaxolol as initial treatment for glaucoma.The British journal of ophthalmology · 1998Trial
- Obstructive Lung Disease among Patients Performing Spirometry in a Tertiary Care Centre: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2022Article
- Geographical distribution of COPD prevalence in Europe, estimated by an inverse distance weighting interpolation technique.International journal of chronic obstructive pulmonary disease · 2018Article
- Epidemiology and management of common pulmonary diseases in older persons.The journals of gerontology. Series A, Biological sciences and medical sciences · 2012Review
- Prevalence and risk factors for unrecognized obstructive lung disease among urban drug users.International journal of chronic obstructive pulmonary disease · 2011Article
- The efficacy of spirometry as a screening tool in detection of air flow obstruction.The open respiratory medicine journal · 2010Article
- Lung function in young adults predicts airflow obstruction 20 years later.The American journal of medicine · 2010Article
- Article
- Article
- Diagnosis of airway obstruction in primary care in the UK: the CADRE (COPD and Asthma Diagnostic/management REassessment) programme 1997-2001.International journal of chronic obstructive pulmonary disease · 2006Article
- Health-related quality of life is related to COPD disease severity.Health and quality of life outcomes · 2005Article
- Prevalence of obstructive lung disease in a general population sample: the NICECOPD study.European journal of epidemiology · 2005Article
- Overcoming gaps in the management of asthma in older patients: new insights.Drugs & aging · 2005Review
- Underdiagnosed asthma in South Australia.Thorax · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic airways obstruction is common in adults and the elderly. To investigate the possibility that older adults with obstructive airways disease frequently do not receive appropriate treatment, the respiratory symptoms, medication use, and pulmonary function were studied in a random sample of white adults aged over 45 living in central Manchester, UK.
methodsA postal questionnaire survey was performed on 783 men and women aged 45 years and over selected from GP lists by random number tables. Subjects completing the questionnaire were invited to attend for pulmonary function testing and methacholine challenge (Newcastle dosimeter method).
resultsThe questionnaire response rate was 92.3% (723 subjects). The mean age of the population was 66.1 years and 57.2% were women; 29.2% were current smokers and 37.3% were ex-smokers. Asthma or bronchitis was reported by 30.0%. Two hundred and forty seven representative subjects attended for pulmonary function testing and spirometric evidence of chronic airways obstruction was found in 26.4%. Respiratory symptoms were reported by 76.6% of subjects with chronic airways obstruction; 55.0% had features which may predict potential improvement on treatment (increased non-specific bronchial responsiveness or significant bronchodilator reversibility). However, only 55.4% of subjects with airways obstruction had received a diagnosis of asthma or chronic bronchitis and only 36.9% were using inhaled bronchodilators or steroids.
conclusionsChronic airways obstruction is very common in adults in this inner city population, but is frequently overlooked. Most subjects with chronic airways obstruction are not receiving appropriate treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.