ArticleProceedings of the National Academy of Sciences of the United States of America1996
Mitochondria are selective targets for the protective effects of heat shock against oxidative injury.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 402 citations in OpenAlex.
- The function of carnosic acid in lipopolysaccharides-induced hepatic and intestinal inflammation in poultry.Poultry science · 2024Article
- Hsp70 in Redox Homeostasis.Cells · 2022Review
- Bacopaside-I Alleviates the Detrimental Effects of Acute Paraquat Intoxication in the Adult Zebrafish Brain.Neurochemical research · 2021Article
- Chronic heat stress regulates the relation between heat shock protein and immunity in broiler small intestine.Scientific reports · 2020Article
- Endothelial extracellular vesicles contain protective proteins and rescue ischemia-reperfusion injury in a human heart-on-chip.Science translational medicine · 2020Article
- Article
- Toxicopathological studies on the effects of T-2 mycotoxin and their interaction in juvenile goats.PloS one · 2020Article
- The still uncertain identity of the channel-forming unit(s) of the mitochondrial permeability transition pore.Cell calcium · 2018Review
- Hsp70 Suppresses Mitochondrial Reactive Oxygen Species and Preserves Pulmonary Microvascular Barrier Integrity Following Exposure to Bacterial Toxins.Frontiers in immunology · 2018Article
- Toxicity evaluation of vinasse and biosolid samples in diplopod midgut: heat shock protein in situ localization.Environmental science and pollution research international · 2017Article
- Extremely low frequency electromagnetic fields stimulation modulates autoimmunity and immune responses: a possible immuno-modulatory therapeutic effect in neurodegenerative diseases.Neural regeneration research · 2016Review
- Targeting Hsp70: A possible therapy for cancer.Cancer letters · 2016Review
- Heat shock protein concentration and clarity of porcine lenses incubated at elevated temperatures.Molecular vision · 2016Article
- Small pelagics in a changing ocean: biological responses of sardine early stages to warming.Conservation physiology · 2016Article
- Promoting Neuronal Tolerance of Diabetic Stress: Modulating Molecular Chaperones.International review of neurobiology · 2016Review
- A pharmacological investigation of Hippophae salicifolia (HS) and Hippophae rhamnoides turkestanica (HRT) against multiple stress (C-H-R): an experimental study using rat model.Cell stress & chaperones · 2015Article
- Heat shock protein 70.1 (Hsp70.1) affects neuronal cell fate by regulating lysosomal acid sphingomyelinase.The Journal of biological chemistry · 2014Article
- Thermal sensation and cell adaptability.International journal of biometeorology · 2014Article
- Article
- Proteomic analysis of cellular response induced by multi-walled carbon nanotubes exposure in A549 cells.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat shock (HS) proteins (HSPs) induce protection against a number of stresses distinct from HS, including reactive oxygen species. In the human premonocytic line U937, we investigated in whole cells the effects of preexposure to HS and exposure to hydrogen peroxide (H2O2) on mitochondrial membrane potential, mass, and ultrastructure. HS prevented H2O2-induced alterations in mitochondrial membrane potential and cristae formation while increasing expression of HSPs and the protein product of bcl-2. Protection correlated best with the expression of the 70-kDa HSP, hsp70. We propose that mitochondria represent a selective target for HS-mediated protection against oxidative injury.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.