Trial reportBMJ (Clinical research ed.)1996
Efficacy of a small single dose of oral dexamethasone for outpatient croup: a double blind placebo controlled clinical trial.
Trial report in BMJ (Clinical research ed.), 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 6 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- Glucocorticoids for croup in children.The Cochrane database of systematic reviews · 2023Pooled it
- Glucocorticoids for croup in children.The Cochrane database of systematic reviews · 2018Pooled it
- Croup.BMJ clinical evidence · 2014Pooled it
- Duration of symptoms of respiratory tract infections in children: systematic review.BMJ (Clinical research ed.) · 2013Pooled it
- Croup.BMJ clinical evidence · 2009Pooled it
- Role of glucocorticoids in treating croup.Canadian family physician Medecin de famille canadien · 2001Pooled it
- Remote, bivariate prior elicitation for a Bayesian non-inferiority randomized controlled trial.Trials · 2026Trial
- The comparative effectiveness of prednisolone and dexamethasone for children with croup: a community-based randomized trial.Clinical pediatrics · 2013Trial
- Storytelling as a communication tool for health consumers: development of an intervention for parents of children with croup. Stories to communicate health information.BMC pediatrics · 2010Trial
- Prednisolone versus dexamethasone in croup: a randomised equivalence trial.Archives of disease in childhood · 2006Trial
- Double blind placebo controlled trial of nebulised budesonide for croup.Archives of disease in childhood · 1997Trial
- Article
- Protective role ofCurrent research in physiology · 2021Article
- Prehospital dexamethasone administration in children with croup: a medical record review.Open access emergency medicine : OAEM · 2018Article
- Acute Respiratory Distress in Children: Croup and Acute Asthma.Indian journal of pediatrics · 2015Review
- Local production of CCL3, CCL11, and IFN-γ correlates with disease severity in murine parainfluenza virus infection.Virology journal · 2013Article
- Introduction to Clinical Answers: Croup.Evidence-based child health : a Cochrane review journal · 2012Article
- Local production of inflammatory mediators during childhood parainfluenza virus infection.The Pediatric infectious disease journal · 2010Article
- A cluster randomized controlled trial comparing three methods of disseminating practice guidelines for children with croup [ISRCTN73394937].Implementation science : IS · 2006Article
- Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection.Antimicrobial agents and chemotherapy · 2006Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the efficacy of a single dose of oral dexamethasone 0.15 mg/kg in children with mild croup not admitted to hospital.
designDouble blind, randomised, placebo controlled clinical trial.
settingThe emergency department of a tertiary paediatric hospital. SUBJECTS: 100 children aged 4-122 months presenting with mild croup.
interventionA single oral dose of dexamethasone 0.15 mg/kg or placebo.
main outcome measureReturn to medical care with ongoing croup.
resultsBaseline characteristics of the two treatment groups were similar. Eight children (all from the placebo group) returned to medical care with ongoing croup, one being admitted. There was no reported difference in duration of croup symptoms, duration of viral symptoms, or rate of return to medical care for other reasons.
conclusionOral dexamethasone in a dose of 0.15 mg/kg is effective in reducing return to medical care with ongoing croup in children with mild croup.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.