ArticleThe Biochemical journal1996
Evidence for specific annexin I-binding proteins on human monocytes.
Article in The Biochemical journal, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 54 citations in OpenAlex.
- Low Annexin A1 level in HTLV-1 infected patients is a potential biomarker for the clinical progression and diagnosis of HAM/TSP.BMC infectious diseases · 2021Article
- Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner.Cell death & disease · 2021Article
- Annexin A1: shifting the balance towards resolution and repair.Biological chemistry · 2016Review
- Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics.British journal of pharmacology · 2009Review
- Annexin-A1: a pivotal regulator of the innate and adaptive immune systems.British journal of pharmacology · 2008Review
- Macrophage surface expression of annexins I and II in the phagocytosis of apoptotic lymphocytes.Molecular biology of the cell · 2004Article
- Dexamethasone enhances interaction of endogenous annexin 1 with L-selectin and triggers shedding of L-selectin in the monocytic cell line U-937.British journal of pharmacology · 2003Article
- Dexamethasone induces the secretion of annexin I in immature lymphoblastic cells by a calcium-dependent mechanism.Molecular and cellular biochemistry · 2002Article
- 17beta-estradiol promotes the synthesis and the secretion of annexin I in the CCRF-CEM human cell line.Mediators of inflammation · 2001Article
- Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics.The American journal of pathology · 2001Article
- Glucocorticoids act within minutes to inhibit recruitment of signalling factors to activated EGF receptors through a receptor-dependent, transcription-independent mechanism.British journal of pharmacology · 2000Article
- Annexin I and dexamethasone effects on phospholipase and cyclooxygenase activity in human synoviocytes.Mediators of inflammation · 2000Article
- The inhibitory effect of dexamethasone on lymphocyte adhesion molecule expression and intercellular aggregation is not mediated by lipocortin 1.Clinical and experimental immunology · 1999Article
- Differential modulation of annexin I binding sites on monocytes and neutrophils.Mediators of inflammation · 1999Article
- Glucocorticoid inhibition of adjuvant arthritis synovial macrophage nitric oxide production: role of lipocortin 1.Clinical and experimental immunology · 1998Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Recombinant human annexin I and a monoclonal antibody specific for this protein (mAb 1B) were used to investigate surface binding of this member of the annexin family of proteins to peripheral blood monocytes. Flow cytometric analysis demonstrated trypsin-sensitive, saturable binding of annexin I to human peripheral blood monocytes but not to admixed lymphocytes. A monoclonal antibody that blocks the anti-phospholipase activity of annexin I also blocked its binding to monocytes. These findings suggest the presence of specific binding sites on monocytes. Furthermore, surface iodination, immunoprecipitation and SDS/PAGE analysis were used to identify two annexin I-binding proteins on the surface of monocytes with molecular masses of 15 kDa and 18 kDa respectively. The identification and characterization of these annexin I-binding molecules should help us to better understand the specific interactions of annexin I with monocytes that lead to down-regulation of pro-inflammatory cell functions.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.