ArticlePlant physiology1996
The Arabidopsis profilin gene family. Evidence for an ancient split between constitutive and pollen-specific profilin genes.
Article in Plant physiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 125 citations in OpenAlex.
- Cytoskeletal control of development and environmental adaptation in plants.Science China. Life sciences · 2026Review
- Profilin and Its Isoforms: Unravelling the Functional Diversity Across Life Forms.Current protein & peptide science · 2026Review
- Redox dynamics in seeds ofFrontiers in plant science · 2024Article
- Functional Characterization of anMolecules (Basel, Switzerland) · 2022Article
- Genome-Wide Identification and Characterization of Actin-Depolymerizing Factor (International journal of molecular sciences · 2020Article
- iTRAQ-Based Quantitative Proteomic Analysis of the Arabidopsis MutantInternational journal of molecular sciences · 2020Article
- Analysis of Pollen Allergens in Lily by Transcriptome and Proteome Data.International journal of molecular sciences · 2019Article
- Cofilin and profilin: partners in cancer aggressiveness.Biophysical reviews · 2018Review
- A profilin gene promoter from switchgrass (Panicum virgatum L.) directs strong and specific transgene expression to vascular bundles in rice.Plant cell reports · 2018Article
- Domestication-driven Gossypium profilin 1 (GhPRF1) gene transduces early flowering phenotype in tobacco by spatial alteration of apical/floral-meristem related gene expression.BMC plant biology · 2016Article
- Profilin-Dependent Nucleation and Assembly of Actin Filaments Controls Cell Elongation in Arabidopsis.Plant physiology · 2016Article
- Arabidopsis plants deficient in constitutive class profilins reveal independent and quantitative genetic effects.BMC plant biology · 2015Article
- Article
- Root hairs.The arabidopsis book · 2014Article
- Profilin as a regulator of the membrane-actin cytoskeleton interface in plant cells.Frontiers in plant science · 2013Review
- Characterization of PROFILIN genes from allotetraploid (Gossypium hirsutum) cotton and its diploid progenitors and expression analysis in cotton genotypes differing in fiber characteristics.Molecular biology reports · 2012Article
- Multiple actin isotypes in plants: diverse genes for diverse roles?Frontiers in plant science · 2012Article
- Characterization of profilin polymorphism in pollen with a focus on multifunctionality.PloS one · 2012Article
- Parallel up-regulation of the profilin gene family following independent domestication of diploid and allopolyploid cotton (Gossypium).Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Arabidopsis VILLIN1 and VILLIN3 have overlapping and distinct activities in actin bundle formation and turnover.The Plant cell · 2010Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Profilin is a ubiquitous eukaryotic protein that regulates the actin cytoskeleton and recently has been identified as a potent allergen in pollen. We examined the profilin gene family in the model plant, Arabidopsis thaliana, and found that it contained approximately 8 to 10 members. Four distinct profilin sequences, three cDNAs, PRF1, PRF2, and PRF3, and two genomic clones, PRF1 and PRF4, were isolated and characterized. These genes encoded four distinct profilin isoforms of 131 to 134 amino acids. Northern and reverse-transcriptase polymerase chain reaction analyses demonstrated that Arabidopsis PRF1 was expressed in all major plant organs, whereas PRF4 was specifically expressed in mature pollen. Gene trees constructed from amino acid sequence data revealed the presence of two ancient, distinct profilin gene classes in plants. PRF4 was in a class with previously identified pollen-specific profilins from monocot and dicot species. PRF1, PRF2, PRF3, and a distant dicot sequence formed a separate novel class, suggesting an ancient separation of plant profilins based on regulation and perhaps function. The coevolution of plant actin and profilin classes with similar patterns of expression is discussed. The similarity of plant, fungal, protist, insect, and nematode profilins and their extreme divergence from the vertebrate profilins has striking implications for the evolution of fungal-spore- and plant-pollen-profilins as allergens.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.