Is interleukin 17, an inducible cytokine that stimulates production of other cytokines, merely a redundant player in a sea of other biomolecules?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed.

1. The Influence of Interleukin 17A and IL17F Polymorphisms on Chronic Periodontitis Disease in Brazilian Patients.Mediators of inflammation · 2015
   Article
2. Pathologic finding of increased expression of interleukin-17 in the synovial tissue of rheumatoid arthritis patients.International journal of clinical and experimental pathology · 2013
   Article
3. The effects of a novel adjuvant complex/Eimeria profilin vaccine on the intestinal host immune response against live E. acervulina challenge infection.Vaccine · 2010
   Article
4. Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans.Immunological reviews · 2008
   Review
5. Antigen-specific tolerogenic and immunomodulatory strategies for the treatment of autoimmune arthritis.Seminars in arthritis and rheumatism · 2008
   Review
6. IL-23 induces human osteoclastogenesis via IL-17 in vitro, and anti-IL-23 antibody attenuates collagen-induced arthritis in rats.Arthritis research & therapy · 2007
   Article
7. Age-dependent cell death and the role of ATP in hydrogen peroxide-induced apoptosis and necrosis.Proceedings of the National Academy of Sciences of the United States of America · 2006
   Article
8. Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.Journal of human genetics · 2003
   Article
9. The molecular mechanism of osteoclastogenesis in rheumatoid arthritis.Arthritis research · 2002
   Review
10. Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family.Proceedings of the National Academy of Sciences of the United States of America · 2000
    Article
11. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis.The Journal of clinical investigation · 1999
    Article
12. Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice.The Journal of experimental medicine · 1997
    Article
13. Involvement of Interleukin (IL) 8 receptor in negative regulation of myeloid progenitor cells in vivo: evidence from mice lacking the murine IL-8 receptor homologue.The Journal of experimental medicine · 1996
    Article

Corrections and comments

• Comment on
  T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines.1996

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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