ArticleThe EMBO journal1996
A two-component histidine kinase gene that functions in Dictyostelium development.
Article in The EMBO journal, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed.
- Review
- Article
- What do archaeal and eukaryotic histidine kinases sense?F1000Research · 2019Review
- Diversity and Evolution of Sensor Histidine Kinases in Eukaryotes.Genome biology and evolution · 2019Article
- Cell-type specific RNA-Seq reveals novel roles and regulatory programs for terminally differentiated Dictyostelium cells.BMC genomics · 2018Article
- Genetic control of morphogenesis in Dictyostelium.Developmental biology · 2015Review
- Cell signaling during development of Dictyostelium.Developmental biology · 2014Review
- Loss of the histidine kinase DhkD results in mobile mounds during development of Dictyostelium discoideum.PloS one · 2013Article
- BzpF is a CREB-like transcription factor that regulates spore maturation and stability in Dictyostelium.Developmental biology · 2011Article
- Autophagic cell death in Dictyostelium requires the receptor histidine kinase DhkM.Molecular biology of the cell · 2010Article
- Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP.The Biochemical journal · 2007Article
- High-throughput analysis of spatio-temporal dynamics in Dictyostelium.Genome biology · 2007Article
- Peptide signaling during terminal differentiation of Dictyostelium.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
- Genome-wide analyses of Escherichia coli gene expression responsive to the BaeSR two-component regulatory system.Journal of bacteriology · 2005Article
- An orderly retreat: Dedifferentiation is a regulated process.Proceedings of the National Academy of Sciences of the United States of America · 2004Article
- Phenotype microarray analysis of Escherichia coli K-12 mutants with deletions of all two-component systems.Journal of bacteriology · 2003Article
- Isolation and functional analysis of a gene, tcsB, encoding a transmembrane hybrid-type histidine kinase from Aspergillus nidulans.Applied and environmental microbiology · 2002Article
- A user's guide to restriction enzyme-mediated integration in Dictyostelium.Journal of muscle research and cell motility · 2002Review
- Osmotic stress-dependent serine phosphorylation of the histidine kinase homologue DokA.BMC biochemistry · 2001Article
- A novel two-component hybrid molecule regulates vascular morphogenesis of the Arabidopsis root.Genes & development · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
A mutant which failed to complete development was isolated from a population of cells that had been subjected to insertional mutagenesis using restriction enzyme-mediated integration. The disrupted gene, dhkA, encodes the conserved motifs of a histidine kinase as well as the response regulator domain. It is likely that the histidine in DhkA is autophosphorylated and the phosphate passed to one or more response regulators. Such two-component systems function in a variety of bacterial signal transduction pathways and have been characterized recently in yeast and Arabidopsis. In Dictyostelium, we found that DhkA functions both in the regulation of prestalk gene expression and in the control of the terminal differentiation of prespore cells.
Indexed as
Identifiers
8670894PMC452090What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.