Evidence map›Paper›PMID 8667290›Full record

ArticleJournal of comparative physiology. A, Sensory, neural, and behavioral physiology1996

Patch-clamp study on membrane properties and transmitter activated currents of rabbit area postrema neurons.

K Jahn, J Bufler, A Weindl, T Arzberger, H Hatt

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Area postrema neurons are modulated by the adipocyte hormone adiponectin.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006
    Article
  2. Article
  3. Article
  4. Orexin-A depolarizes dissociated rat area postrema neurons through activation of a nonselective cationic conductance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

K JahnNeurologische Klinik, Technischen Universität München, Germany.
J Bufler
A Weindl
T Arzberger
H Hatt
Technical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Using the patch-clamp technique in combination wit sliced tissue preparation the membrane properties of newborn rabbit area postrema neurons were investigated. The neurons responded upon depolarization with a fast Na+-current followed by an inactivating and non-inactivating K+-current. GABA-activated currents were investigated resulting in a large C1-(-)conductance, indicating the expression of GABAA-receptors. The expression of glutamate receptor mRNA was studied by in situ hybridization and electrophysiological measurements of these receptors by means of the patch-clamp technique. As a main result it was found that ionotropic glutamate receptors in the area postrema are composed of "flop" variants of the GluA-, GluB- and GluC-subunits.

Indexed as

AnimalsBase SequenceBrain StemCell MembraneCerebral VentriclesExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsHistocytochemistryIn Situ HybridizationIn Vitro TechniquesIon Channel GatingIon ChannelsMembrane PotentialsMolecular Sequence DataNeuronsNeurotransmitter AgentsExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsIon ChannelsNeurotransmitter AgentsReceptors, GABAReceptors, GlutamateRNA Probes

Identifiers

PMID8667290
OpenAlexW1992563367

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.