ArticleCalcified tissue international1996
Bone mass in Parkinson's disease: a study with three methods.
Article in Calcified tissue international, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Bone health in Parkinson's disease: a systematic review and meta-analysis.Journal of neurology, neurosurgery, and psychiatry · 2014Pooled it
- Prevalence and risk factors of osteoporosis in patients with Parkinson's disease.Rheumatology international · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent reports suggest the presence of osteopenia in a high percentage of patients with Parkinson's disease (PD). These data contrast with previous reports of our group, perhaps due to the different methods used. We studied bone mass in 52 PD patients (28 males, 24 females) and in 80 age- and sex-matched controls (40 males, 40 females) who had no other disease that could affect bone mass. We measured the totally body bone mineral content (TBBMC) and the ultrasound bone velocity (UBV) of transmission in phalanx, and performed metacarpal radiogrammetry with computerized radiography (CCT). We also measured serum levels of total alkaline phosphatase and tartrate-resistant acid phosphatase, which were significantly increased in PD patients compared with controls (P < 0.0001). TBBMC was significantly lower in males (P < 0.05) and females (P < 0.05) with PD with respect to their controls. CCT did not differ significantly between the study groups. UBV was significantly lower in males with PD (P < 0.005), but similar in female PD and controls. These data suggest that the changes reported in bone mass in PD patients can depend on the sex and the study methods. We only found severe osteopenia in one male (3.6%) and five females (20.8%) with PD according to z-score. Only in women was no relationship found between TBBMC and severity of PD.
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Registered trials
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