Evidence map›Paper›PMID 8661719›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society1996

Generation and mapping of Mus spretus strain-specific markers for rapid genomic scanning.

R Elango, L Riba, D Housman, K Hunter

Abstract read
PubMed Publisher
In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Generation of gene knockout mice by ES cell microinjection.Current protocols in cell biology · 2009
    Article
  2. IRS-PCR-based genetic mapping of the huntingtin interacting protein gene (HIP1) on mouse chromosome 5.Mammalian genome : official journal of the International Mammalian Genome Society · 1998
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

R ElangoCenter for Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
L Riba
D Housman
K Hunter
Center for Cancer Research · USMassachusetts Institute of Technology · US

Funding

STUDY OF THE FIBRONECTIN FUNCTIONP01HL041484 · NHLBI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI KRIEGER, MONTY · 1988 to 2000
$2.7M
HIGH THROUGHPUT LOW COST IRS-PCR BASED GENOTYPINGR01HG000299 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HOUSMAN, DAVID E · 1990 to 2001
$1.1M
NHGRI NIH HHS HG00299NHLBI NIH HHS HL41484
6 · The paper itself

Abstract

We describe here a set of genetic markers, based on IRS-PCR amplification difference, that are specifically designed for efficient, high throughput genetic mapping in [(M. domesticus x wild-derived) F1 x M. domesticus] interspecific backcrosses. 146 new genetic loci have been mapped, and strain distribution for these markers has been determined in 96 mouse strains. 103 (81%) of 127 tested markers are present only in one or more wild-derived strains, but absent in 76 other commonly used strains, demonstrating their utility in a variety of mouse pair combinations. Because of the ease of genotyping with this marker set, rapid genome scans for complex genetic trait loci involving crosses between wild-derived strains and other commonly used strains can now be carried out efficiently with large numbers of animals.

Indexed as

Genetic MarkersGenomeAnimalsChromosome MappingCrosses, GeneticFemaleHybridization, GeneticMaleMiceMice, Inbred C57BLMice, Inbred StrainsMuridaePolymerase Chain ReactionSubtraction TechniqueGenetic Markers

Identifiers

PMID8661719
OpenAlexW2075948371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.