Evidence for genetic anticipation in non-Mendelian diseases.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed, 42 citations in OpenAlex.

1. Association of Acquired and Heritable Factors With Intergenerational Differences in Age at Symptomatic Onset of Alzheimer Disease Between Offspring and Parents With Dementia.JAMA network open · 2019
   Article
2. Evolvability of Amyloidogenic Proteins in Human Brain.Journal of Alzheimer's disease : JAD · 2018
   Article
3. Is there a genetic anticipation in breast and/or ovarian cancer families with the germline c.3481_3491del11 mutation?Familial cancer · 2018
   Article
4. TNFSF4 Gene Variations Are Related to Early-Onset Autoimmune Thyroid Diseases and Hypothyroidism of Hashimoto's Thyroiditis.International journal of molecular sciences · 2016
   Article
5. Genetic anticipation in BRCA1/BRCA2 families after controlling for ascertainment bias and cohort effect.Cancer · 2016
   Article
6. Differences in Gene-Gene Interactions in Graves' Disease Patients Stratified by Age of Onset.PloS one · 2016
   Article
7. Association between age at diagnosis of Graves' disease and variants in genes involved in immune response.PloS one · 2013
   Article
8. Earlier age of onset of BRCA mutation-related cancers in subsequent generations.Cancer · 2012
   Article
9. Genetic anticipation is associated with telomere shortening in hereditary breast cancer.PLoS genetics · 2011
   Article
10. Anticipation in families with chronic lymphocytic leukemia and other lymphoproliferative disorders.Translational oncogenomics · 2010
    Article
11. Anticipation in familial pancreatic cancer.Gut · 2006
    Article
12. BRCA1 and BRCA2 germline mutational spectrum and evidence for genetic anticipation in Portuguese breast/ovarian cancer families.Familial cancer · 2006
    Article
13. Statistical evaluation of age-at-onset anticipation: a new test and evaluation of its behavior in realistic applications.American journal of human genetics · 1998
    Article
14. Search for unstable DNA in schizophrenia families with evidence for genetic anticipation.American journal of human genetics · 1996
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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