ArticleJournal of bacteriology1996
Heat shock activation of the groESL operon of Agrobacterium tumefaciens and the regulatory roles of the inverted repeat.
Article in Journal of bacteriology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 47 citations in OpenAlex.
- Biologically Synthesized Gold Nanoparticles Ameliorate Cold and Heat Stress-Induced Oxidative Stress in Escherichia coli.Molecules (Basel, Switzerland) · 2016Article
- Characterization and expression analysis of the groESL operon of Bartonella bacilliformis.Gene · 2005Article
- Replicon-specific regulation of small heat shock genes in Agrobacterium tumefaciens.Journal of bacteriology · 2004Article
- Sinorhizobium meliloti RpoH1 is required for effective nitrogen-fixing symbiosis with alfalfa.Molecular genetics and genomics : MGG · 2004Article
- CIRCE is not involved in heat-dependent transcription of groESL but in stabilization of the mRNA 5'-end in Rhodobacter capsulatus.Nucleic acids research · 2004Article
- Heat shock proteome of Agrobacterium tumefaciens: evidence for new control systems.Journal of bacteriology · 2002Article
- DnaK chaperone-mediated control of activity of a sigma(32) homolog (RpoH) plays a major role in the heat shock response of Agrobacterium tumefaciens.Journal of bacteriology · 2001Article
- Transcriptional analysis of major heat shock genes of Helicobacter pylori.Journal of bacteriology · 2000Article
- Differential and independent roles of a sigma(32) homolog (RpoH) and an HrcA repressor in the heat shock response of Agrobacterium tumefaciens.Journal of bacteriology · 1999Article
- The CIRCE element and its putative repressor control cell cycle expression of the Caulobacter crescentus groESL operon.Journal of bacteriology · 1998Article
- Regulation of the dnaK operon of Streptomyces coelicolor A3(2) is governed by HspR, an autoregulatory repressor protein.Journal of bacteriology · 1997Article
- The GroE chaperonin machine is a major modulator of the CIRCE heat shock regulon of Bacillus subtilis.The EMBO journal · 1997Article
- Cloning, nucleotide sequence, and regulatory analysis of the Nitrosomonas europaea dnaK gene.Applied and environmental microbiology · 1997Article
- Cloning and characterization of two groESL operons of Rhodobacter sphaeroides: transcriptional regulation of the heat-induced groESL operon.Journal of bacteriology · 1997Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deletions were constructed in the conserved inverted repeat (IR) found in the groESL operon of Agrobacterium tumefaciens and in many other groE and dnaK operons and genes in eubacteria. These deletions affected the level of expression of the operon and the magnitude of its heat shock activation. The IR seems to operate at the DNA level, probably as an operator site that binds a repressor under non-heat shock conditions. The IR was also found to function at the mRNA level, since under non-heat shock conditions transcripts containing deletions of one side of the IR had longer half-lives than did transcripts containing the wild-type IR. Under heat shock conditions, the half-life of the mRNA was unaffected by this deletion because of heat shock-dependent cleavage. However, the groESL operon was found to be heat shock activated even after most of the IR was deleted. This observation, together with the fact that the groESL operon of A. tumefaciens was heat shock activated in Escherichia coli and vice versa, suggests that a heat shock promoter regulates the heat shock activation of this operon. The primary role of the IR appears to be in reducing the MRNA levels from this promoter under non-heat shock conditions.
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