ArticleJournal of virology1996
The human cytomegalovirus UL94 open reading frame encodes a conserved herpesvirus capsid/tegument-associated virion protein that is expressed with true late kinetics.
Article in Journal of virology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 73 citations in OpenAlex.
- Human herpesvirus 6B U65 binds to histone proteins and suppresses interferon production.Journal of virology · 2025Article
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- The A137R Protein of African Swine Fever Virus Inhibits Type I Interferon Production via the Autophagy-Mediated Lysosomal Degradation of TBK1.Journal of virology · 2022Article
- Review
- Human Cytomegalovirus Protein UL94 Targets MITA to Evade the Antiviral Immune Response.Journal of virology · 2020Article
- The Product of the Herpes Simplex Virus 2 UL16 Gene Is Critical for the Egress of Capsids from the Nuclei of Infected Cells.Journal of virology · 2017Article
- Domain Interaction Studies of Herpes Simplex Virus 1 Tegument Protein UL16 Reveal Its Interaction with Mitochondria.Journal of virology · 2017Article
- ORF33 and ORF38 of Kaposi's Sarcoma-Associated Herpesvirus Interact and Are Required for Optimal Production of Infectious Progeny Viruses.Journal of virology · 2016Article
- A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny viruses.Journal of virology · 2015Article
- Identification of human cytomegalovirus genes important for biogenesis of the cytoplasmic virion assembly complex.Journal of virology · 2014Article
- Review
- Functional annotation of human cytomegalovirus gene products: an update.Frontiers in microbiology · 2014Review
- Elucidation of the block to herpes simplex virus egress in the absence of tegument protein UL16 reveals a novel interaction with VP22.Journal of virology · 2014Article
- Inactivation of enveloped virus by laser-driven protein aggregation.Journal of biomedical optics · 2012Article
- Replication kinetics of duck enteritis virus UL16 gene in vitro.Virology journal · 2012Article
- Regulated interaction of tegument proteins UL16 and UL11 from herpes simplex virus.Journal of virology · 2012Article
- Interaction between the human cytomegalovirus tegument proteins UL94 and UL99 is essential for virus replication.Journal of virology · 2012Article
- Deletion of UL21 causes a delay in the early stages of the herpes simplex virus 1 replication cycle.Journal of virology · 2012Article
- The human cytomegalovirus (HCMV) tegument protein UL94 is essential for secondary envelopment of HCMV virions.Journal of virology · 2012Article
- Direct and specific binding of the UL16 tegument protein of herpes simplex virus to the cytoplasmic tail of glycoprotein E.Journal of virology · 2011Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
In this report, we provide a detailed characterization of the human cytomegalovirus (HCMV) UL94 gene product. Northern (RNA) blot analysis of infected cell RNA demonstrated that UL94 message was found only at late times of infection and was not synthesized in the presence of the viral DNA replication inhibitor ganciclovir. Expression of the UL94 open reading frame in vitro and in vivo yielded a protein with the predicted molecular mass of 36 kDa. A monoclonal antibody raised to a UL94-specific peptide reacted specifically with a 36-kDa protein in HCMV-infected fibroblasts. This protein was found only at late times of infection and was also present in purified HCMV virions. Fractionation of purified virions and HCMV-infected cells revealed an association of UL94 immunoreactivity with the capsid/tegument and nuclear fractions, respectively. The evolutionary conservation of UL94 protein sequence and an analysis of potential functional regions of the protein are discussed.
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