ArticleProceedings of the National Academy of Sciences of the United States of America1996
Two mitochondrial group I introns in a metazoan, the sea anemone Metridium senile: one intron contains genes for subunits 1 and 3 of NADH dehydrogenase.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43 citing papers in PubMed, 106 citations in OpenAlex.
- Mitogenomic organization and characteristics of deep-sea pelagic ostracods from both polar regions.BMC genomics · 2026Article
- Complete mitochondrial genomes of the black coralsZooKeys · 2024Article
- Mito-nuclear discordance within Anthozoa, with notes on unique properties of their mitochondrial genomes.Scientific reports · 2023Article
- Confirmation of the first intronic sequence in the bivalvian mitochondrial genome ofBiology letters · 2022Article
- Unprecedented frequency of mitochondrial introns in colonial bilaterians.Scientific reports · 2022Article
- Comparative Analysis of the Mitochondrial Genome ofFrontiers in genetics · 2022Article
- Organellar Introns in Fungi, Algae, and Plants.Cells · 2021Review
- The Mitochondrial Genome of the Sea AnemoneLife (Basel, Switzerland) · 2021Article
- The first mitochondrial genome of scale insects (Hemiptera: Coccoidea).Mitochondrial DNA. Part B, Resources · 2019Article
- Giant group I intron in a mitochondrial genome is removed by RNA back-splicing.BMC molecular biology · 2019Article
- Genome streamlining via complete loss of introns has occurred multiple times in lichenized fungal mitochondria.Ecology and evolution · 2019Article
- The mitochondrial genomes of sarcoptiform mites: are any transfer RNA genes really lost?BMC genomics · 2018Article
- The mitochondrial genome of a sea anemoneEcology and evolution · 2017Article
- Multiple introns in a deep-sea Annelid (Decemunciger: Ampharetidae) mitochondrial genome.Scientific reports · 2017Article
- Loss and Gain of Group I Introns in the MitochondrialZoological studies · 2017Article
- Article
- Animal Mitochondrial DNA as We Do Not Know It: mt-Genome Organization and Evolution in Nonbilaterian Lineages.Genome biology and evolution · 2016Article
- A mitochondrial intron in a verongid sponge.Journal of molecular evolution · 2015Article
- Characterization and localization of mitochondrial DNA-encoded tRNAs and nuclear DNA-encoded tRNAs in the sea anemone Metridium senile.Current genetics · 2013Article
- The rhizome of life: what about metazoa?Frontiers in cellular and infection microbiology · 2012Review
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3 authors at 1 institution in 1 country.
Funding
Abstract
Mitochondrial genes for cytochrome c oxidase subunit I (COI) and NADH dehydrogenase subunit 5 (ND5) of the sea anemone Metridium senile (phylum Cnidaria) each contain a group I intron. This is in contrast to the reported absence of introns in all other metazoan mtDNAs so far examined. The ND5 intron is unusual in that it ends with A and contains two genes (ND1 and ND3) encoding additional subunits of NADH dehydrogenase. Correctly excised ND5 introns are not circularized but are precisely cleaved near their 3' ends and polyadenylylated to provide bicistronic transcripts of ND1 and ND3. COI introns, which encode a putative homing endonuclease, circularize, but in a way that retains the entire genome-encoded intron sequence (other group I introns are circularized with loss of a short segment of the intron 5' end). Introns were detected in the COI and ND5 genes of other sea anemones, but not in the COI and ND5 genes of other cnidarians. This suggests that the sea anemone mitochondrial introns may have been acquired relatively recently.
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