ArticleProceedings of the National Academy of Sciences of the United States of America1996
Genes encoding the same three subunits of respiratory complex II are present in the mitochondrial DNA of two phylogenetically distant eukaryotes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 90 citations in OpenAlex.
- Discovery of succinate dehydrogenase candidate fungicides via lead optimization for effective resistance management of3 Biotech · 2022Article
- Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology.Redox biology · 2021Review
- Expression analysis of mammalian mitochondrial ribosomal protein genes.Gene expression patterns : GEP · 2020Article
- An evolutionary, or "Mitocentric" perspective on cellular function and disease.Redox biology · 2020Review
- The assembly of succinate dehydrogenase: a key enzyme in bioenergetics.Cellular and molecular life sciences : CMLS · 2019Review
- Mitochondrial Dysfunctions: A Thread Sewing Together Alzheimer's Disease, Diabetes, and Obesity.Oxidative medicine and cellular longevity · 2019Review
- HIF-1α Stabilization Increases miR-210 Eliciting First Trimester Extravillous Trophoblast Mitochondrial Dysfunction.Frontiers in physiology · 2019Article
- An Assembly Factor Promotes Assembly of Flavinated SDH1 into the Succinate Dehydrogenase Complex.Plant physiology · 2018Article
- Landscape genomics: natural selection drives the evolution of mitogenome in penguins.BMC genomics · 2018Article
- Reference gene selection to determine differences in mitochondrial gene expressions in phosphine-susceptible and phosphine-resistant strains of Cryptolestes ferrugineus, using qRT-PCR.Scientific reports · 2017Article
- SDH6 and SDH7 Contribute to Anchoring Succinate Dehydrogenase to the Inner Mitochondrial Membrane in Arabidopsis thaliana.Plant physiology · 2017Article
- Unexpectedly Streamlined Mitochondrial Genome of the Euglenozoan Euglena gracilis.Genome biology and evolution · 2015Article
- Why chloroplasts and mitochondria retain their own genomes and genetic systems: Colocation for redox regulation of gene expression.Proceedings of the National Academy of Sciences of the United States of America · 2015Review
- Sequence diversity and conservation in factors influencing succinate dehydrogenase flavinylation.Plant signaling & behavior · 2013Review
- Functional and composition differences between mitochondrial complex II in Arabidopsis and rice are correlated with the complex genetic history of the enzyme.Plant molecular biology · 2010Article
- Discovery of the rpl10 gene in diverse plant mitochondrial genomes and its probable replacement by the nuclear gene for chloroplast RPL10 in two lineages of angiosperms.DNA research : an international journal for rapid publication of reports on genes and genomes · 2010Article
- Experimental analysis of the rice mitochondrial proteome, its biogenesis, and heterogeneity.Plant physiology · 2009Article
- The Rhodomonas salina mitochondrial genome: bacteria-like operons, compact gene arrangement and complex repeat region.Nucleic acids research · 2005Article
- Nuclear SDH2-1 and SDH2-2 genes, encoding the iron-sulfur subunit of mitochondrial complex II in Arabidopsis, have distinct cell-specific expression patterns and promoter activities.Plant physiology · 2004Article
- New insights into the respiratory chain of plant mitochondria. Supercomplexes and a unique composition of complex II.Plant physiology · 2003Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although mitochondrial DNA is known to encode a limited number (<20) of the polypeptide components of respiratory complexes I, III, IV, and V, genes for components of complex II [succinate dehydrogenase (ubiquinone); succinate:ubiquinone oxidoreductase, EC 1.3.5.1] are conspicuously lacking in mitochondrial genomes so far characterized. Here we show that the same three subunits of complex II are encoded in the mitochondrial DNA of two phylogenetically distant eukaryotes, Porphyra purpurea (a photosynthetic red alga) and Reclinomonas americana (a heterotrophic zooflagellate). These complex II genes, sdh2, sdh3, and sdh4, are homologs, respectively, of Escherichia coli sdhB, sdhC, and sdhD. In E. coli, sdhB encodes the iron-sulfur subunit of succinate dehydrogenase (SDH), whereas sdhC and sdhD specify, respectively, apocytochrome b558 and a hydrophobic 13-kDa polypeptide, which together anchor SDH to the inner mitochondrial membrane. Amino acid sequence similarities indicate that sdh2, sdh3, and sdh4 were originally encoded in the protomitochondrial genome and have subsequently been transferred to the nuclear genome in most eukaryotes. The data presented here are consistent with the view that mitochondria constitute a monophyletic lineage.
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