ArticleJournal of bacteriology1996
Two transcription factors, Gln3p and Nil1p, use the same GATAAG sites to activate the expression of GAP1 of Saccharomyces cerevisiae.
Article in Journal of bacteriology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 61 citations in OpenAlex.
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- Transcription-dependent spreading of the Dal80 yeast GATA factor across the body of highly expressed genes.PLoS genetics · 2019Article
- Single-cell copy number variant detection reveals the dynamics and diversity of adaptation.PLoS biology · 2018Article
- Systematic identification of factors mediating accelerated mRNA degradation in response to changes in environmental nitrogen.PLoS genetics · 2018Article
- Achieving global perfect homeostasis through transporter regulation.PLoS computational biology · 2017Article
- Nuclear Gln3 Import Is Regulated by Nitrogen Catabolite Repression Whereas Export Is Specifically Regulated by Glutamine.Genetics · 2015Article
- Tor Signaling Regulates Transcription of Amino Acid Permeases through a GATA Transcription Factor Gaf1 in Fission Yeast.PloS one · 2015Article
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- Adaptation to diverse nitrogen-limited environments by deletion or extrachromosomal element formation of the GAP1 locus.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Rapamycin treatment results in GATA factor-independent hyperphosphorylation of the proline utilization pathway activator in Saccharomyces cerevisiae.Eukaryotic cell · 2003Article
- Saccharomyces forkhead protein Fkh1 regulates donor preference during mating-type switching through the recombination enhancer.Genes & development · 2002Article
- Role of glutamine synthetase in nitrogen metabolite repression in Aspergillus nidulans.Journal of bacteriology · 2001Article
- Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia.The Journal of biological chemistry · 2001Article
- TOR modulates GCN4-dependent expression of genes turned on by nitrogen limitation.Journal of bacteriology · 2001Article
- Nitrogen catabolite repression in Saccharomyces cerevisiae.Molecular biotechnology · 1999Review
- Ssy1p and Ptr3p are plasma membrane components of a yeast system that senses extracellular amino acids.Molecular and cellular biology · 1999Article
- The Saccharomyces cerevisiae GATA factors Dal80p and Deh1p can form homo- and heterodimeric complexes.Journal of bacteriology · 1998Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
We present an analysis of the DNA region located upstream of GAP1, the structural gene for the general amino acid permease, which contains the sites required for activation of transcription of this gene in response to the nitrogen source of the growth medium. This gene is not expressed in media containing glutamine, and its transcription is activated in response to Gln3p in cells using glutamate as the source of nitrogen and by Nil1p in cells using urea as the source of nitrogen. We show that full response to both activators requires the presence of two GATAAG sites, as well as the presence of auxiliary sites located in the interval between 602 and 453 bp from the translational start site. The fact that both Gln3p and Nil1p utilize GATAAG sites to activate transcription is reflected in the high homology of the zinc finger regions of the two proteins.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.