Evidence map›Paper›PMID 8633017›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1996

Mapping the protein regions responsible for the functional specificities of the Arabidopsis MADS domain organ-identity proteins.

B A Krizek, E M Meyerowitz

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 176 citations in OpenAlex.

  1. Article
  2. Article
  3. Cracking the Floral Quartet Code: How Do Multimers of MIKCInternational journal of molecular sciences · 2023
    Review
  4. Article
  5. Article
  6. Alternatively splicedHorticulture research · 2020
    Article
  7. Article
  8. Structural Basis for Plant MADS Transcription Factor Oligomerization.Computational and structural biotechnology journal · 2019
    Review
  9. Isolation and Functional Analysis ofFrontiers in plant science · 2018
    Article
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

B A KrizekDivision of Biology, California Institute of Technology, Pasadena 91125, USA.
E M Meyerowitz
California Institute of Technology · US

Funding

NIGMS NIH HHS GM45697
6 · The paper itself

Abstract

The Arabidopsis MADS domain proteins AP1, AP3, PI, and AG specify floral organ identity. All of these proteins contain a MADS domain required for DNA binding and dimerization; a region termed L (linker between MADS domain and K domain), which plays an important role in dimerization specificity; the K domain, named for its similarity to the coiled-coil domain of keratin; and a C-terminal region of unknown function. To determine which regions of these proteins are responsible for their abilities to specify different organs, we have made a number of chimeric MADS box genes. The in vivo function of these chimeric genes was investigated by ectopic expression in transgenic Arabidopsis plants. The four proteins fall into two classes on the basis of regions responsible for their functional specificities. The L region and K domain define the functional specificities of AP3 and PI, while the MADS domain and L region define the functional specificities of AP1 and AG.

Indexed as

Amino Acid SequenceArabidopsisBinding SitesDNA-Binding ProteinsGene Expression Regulation, PlantGenes, PlantGenetic Complementation TestMacromolecular SubstancesMADS Domain ProteinsMicroscopy, Electron, ScanningMolecular Sequence DataMutagenesis, Site-DirectedOrgan SpecificityPhenotypePlant ProteinsPolymerase Chain ReactionDNA-Binding ProteinsMacromolecular SubstancesMADS Domain ProteinsPlant ProteinsRecombinant ProteinsTranscription Factors

Identifiers

PMID8633017
PMCPMC39487
OpenAlexW2018705472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.