ArticleProceedings of the National Academy of Sciences of the United States of America1996
Assignment of Rfp-Y to the chicken major histocompatibility complex/NOR microchromosome and evidence for high-frequency recombination associated with the nucleolar organizer region.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
- Adaptive radiation and structural tailoring of the VietnameseFrontiers in genetics · 2026Article
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- Innate immune genes of the chicken MHC and related regions.Immunogenetics · 2022Review
- New vistas unfold: Chicken MHC molecules reveal unexpected ways to present peptides to the immune system.Frontiers in immunology · 2022Review
- Assessing MHC-B diversity in Silkie chickens.Poultry science · 2020Article
- Advances in methodologies for detecting MHC-B variability in chickens.Poultry science · 2020Review
- Not all birds have a single dominantly expressed MHC-I gene: Transcription suggests that siskins have many highly expressed MHC-I genes.Scientific reports · 2019Article
- Characterization of class II β chain major histocompatibility complex genes in a family of Hawaiian honeycreepers: 'amakihi (Hemignathus virens).Immunogenetics · 2016Article
- Brief review of the chicken Major Histocompatibility Complex: the genes, their distribution on chromosome 16, and their contributions to disease resistance.Poultry science · 2016Review
- Virus and host genomic, molecular, and cellular interactions during Marek's disease pathogenesis and oncogenesis.Poultry science · 2016Review
- A high-density SNP panel reveals extensive diversity, frequent recombination and multiple recombination hotspots within the chicken major histocompatibility complex B region between BG2 and CD1A1.Genetics, selection, evolution : GSE · 2016Article
- Chicken rRNA Gene Cluster Structure.PloS one · 2016Article
- Article
- The peptide motif of the single dominantly expressed class I molecule of the chicken MHC can explain the response to a molecular defined vaccine of infectious bursal disease virus (IBDV).Immunogenetics · 2013Article
- Characteristics of MHC class I genes in house sparrows Passer domesticus as revealed by long cDNA transcripts and amplicon sequencing.Journal of molecular evolution · 2013Article
- Diversity and evolution of the highly polymorphic tandem repeat LEI0258 in the chicken MHC-B region.Immunogenetics · 2013Article
- MHC class IIB exon 2 polymorphism in the Grey partridge (Perdix perdix) is shaped by selection, recombination and gene conversion.PloS one · 2013Article
- Defining the turkey MHC: identification of expressed class I- and class IIB-like genes independent of the MHC-B.Immunogenetics · 2011Article
- Genetic mapping of the major histocompatibility complex in the zebra finch (Taeniopygia guttata).Immunogenetics · 2011Article
- Integrative mapping analysis of chicken microchromosome 16 organization.BMC genomics · 2010Article
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8 authors.
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Abstract
Rfp-Y is a second region in the genome of the chicken containing major histocompatibility complex (MHC) class I and II genes. Haplotypes of Rfp-Y assort independently from haplotypes of the B system, a region known to function as a MHC and to be located on chromosome 16 (a microchromosome) with the single nucleolar organizer region (NOR) in the chicken genome. Linkage mapping with reference populations failed to reveal the location of Rfp-Y, leaving Rfp-Y unlinked in a map containing >400 markers. A possible location of Rfp-Y became apparent in studies of chickens trisomic for chromosome 16 when it was noted that the intensity of restriction fragments associated with Rfp-Y increased with increasing copy number of chromosome 16. Further evidence that Rfp-Y might be located on chromosome 16 was obtained when individuals trisomic for chromosome 16 were found to transmit three Rfp-Y haplotypes. Finally, mapping of cosmid cluster III of the molecular map of chicken MHC genes (containing a MHC class II gene and two rRNA genes) to Rfp-Y validated the assignment of Rfp-Y to the MHC/NOR microchromosome. A genetic map can now be drawn for a portion of chicken chromosome 16 with Rfp-Y, encompassing two MHC class I and three MHC class II genes, separated from the B system by a region containing the NOR and exhibiting highly frequent recombination.
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