Evidence map›Paper›PMID 8628042›Full record

ArticleMedical care1996

A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity.

J Ware, M Kosinski, S D Keller

89 registry-linked trialsAbstract read
PubMed Publisher
In one paragraph

Article in Medical care, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 89 registered trials, which are not on this map. Cited by 7,717 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7,717citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00337350 phase4completednot on this mapstarted 2003, after this paper: background citation

A Double-Blind, Placebo-Controlled Trial of Rosiglitazone for Clozapine Induced Glucose Metabolism Impairment: Bergman's Minimal Model Analysis

TypeinterventionalSponsorMassachusetts General HospitalRan2003 to 2011Enrolled20ConditionsSchizophreniaArmsrosiglitazone, placebo
NCT00595504 phase4completednot on this mapstarted 2008, after this paper: background citation

Phase IV Study of Ramelteon as an Adjunct Therapy in Non-Diabetic Patients With Schizophrenia

TypeinterventionalSponsorMassachusetts General HospitalRan2008 to 2010Enrolled25ConditionsSchizophrenia, Schizoaffective Disorder, Schizophreniform DisordersArmsRamelteon, Placebo
NCT00871299 nacompletednot on this mapstarted 2009, after this paper: background citation

Applying Mindfulness-Based Cognitive Therapy to Treatment Resistant Depression

TypeinterventionalSponsorUniversity of California, San FranciscoRan2009 to 2014Enrolled173ConditionsMajor Depressive DisorderArmsMindfulness Based Cognitive Therapy, Health Enhancement Program and medication management
NCT01069315 nacompletednot on this mapstarted 2006, after this paper: background citation

Fluid Lavage of Open Wounds (FLOW): A Multi-Center, Blinded, Factorial Pilot Trial Comparing Alternative Irrigating Solutions and Pressures in Patients With Open Fractures

TypeinterventionalSponsorMcMaster UniversityRan2006 to 2008Enrolled111ConditionsInfection, Wound Healing Problem, NonunionArmsType of fluid lavage solution, Type of fluid lavage pressure
NCT01307501 nacompletednot on this mapstarted 2012, after this paper: background citation

Evaluating Cryoablation of Metastatic Lung/Pleura Tumors in Patients - Safety and Efficacy

TypeinterventionalSponsorBoston Scientific CorporationRan2012 to 2018Enrolled40ConditionsMetastatic Lung CancerArmsCryoablation
NCT01623843 nacompletednot on this mapstarted 2012, after this paper: background citation

Femoroacetabular Impingement RandomiSed Controlled Trial (FIRST); Sub-study: Femoroacetabular Impingement RandomiSed Controlled Trial With an Embedded Prospective Cohort (FIRST-EPIC)

TypeinterventionalSponsorMcMaster UniversityRan2012 to 2020Enrolled220ConditionsFemoroacetabular ImpingementArmsArthroscopic Lavage, Arthroscopic Osteochondroplasty
NCT01638377 phase4terminatednot on this mapstarted 2012, after this paper: background citation

A Multi-site Study to Disseminate and Evaluate Pharmacotherapy for Alcohol Dependence in Convicted Drinking Drivers

TypeinterventionalSponsorCentre for Addiction and Mental HealthRan2012 to 2014Enrolled2ConditionsAlcohol DependenceArmsNaltrexone, Control
NCT01689064 nacompletednot on this mapstarted 2012, after this paper: background citation

Comparison of the Posterior Septectomy and Stamm Approach to Endoscopic Pituitary Adenoma Resection: A Randomized, Single-blind Trial

TypeinterventionalSponsorUniversity of CalgaryRan2012 to 2014Enrolled55ConditionsPituitary Adenoma, Posterior Septectomy, Stamm Approach, Quality of LifeArmsStamm Approach, Posterior Septectomy
NCT01785485 unknown statusnot on this mapstarted 2013, after this paper: background citation

IMPACT: Integrative Medicine PrimAry Care Trial: A Comparative Effectiveness Study of an Integrative Primary Care Clinic

TypeobservationalSponsorUniversity of ArizonaRan2013 to 2015Enrolled500ConditionsAdult Primary Care PatientsArmsIntegrative medicine primary care model
NCT02227303 nacompletednot on this mapstarted 2014, after this paper: background citation

A Pilot Open Label Clinical Trial to Evaluate the Combined Impact of Two Mobile Health Products on Health Outcomes in Overweight Adults With Type 2 Diabetes

TypeinterventionalSponsorMedidata SolutionsRan2014 to 2015Enrolled23ConditionsType 2 Diabetes MellitusArmslifestyle modification instructional and motivational sessions
NCT02316275 narecruitingnot on this mapstarted 2011, after this paper: background citation

IMpact of Unrestricted ACTIVity Following Mid-Urethral Sling Surgery (I'M ACTIVe): Quality of Life and Cost Implications

TypeinterventionalSponsorCedars-Sinai Medical CenterRan2011 to 2031Enrolled50ConditionsStress Urinary IncontinenceArmsNo post-operative activity restrictions, Standard post-operative activity restriction
NCT02341690 nacompletednot on this mapstarted 2015, after this paper: background citation

The Effectiveness of Smartphone Delivered Interval Walking Training on Physical Activity and Glycemic Control in Patients With Type 2 Diabetes: a Pragmatic Randomized Controlled Trial - Part of The InterWalk Study

TypeinterventionalSponsorUniversity of CopenhagenRan2015 to 2017Enrolled226ConditionsDiabetes Mellitus, Type 2ArmsInterval walking training, control
NCT02384265 nacompletednot on this mapstarted 2012, after this paper: background citation

Financial Incentives and SMS to Improve African American Womens' Glycemic Control: Friends & Relatives Improving the Effectiveness of Networks for Diabetes Support Through Text Messaging (FRIENDS Text)

TypeinterventionalSponsorUniversity of California, Los AngelesRan2012 to 2021Enrolled41ConditionsDiabetes MellitusArmsIM/SMS + Incentive Condition
NCT02399319 naterminatednot on this mapstarted 2014, after this paper: background citation

Prospective Randomized Comparison of Subcutaneous Internal Fixation ("INFIX") and Plating for Pelvic Ring Injuries With Symphysis Disruptions

TypeinterventionalSponsorIndiana UniversityRan2014 to 2016Enrolled4ConditionsAnterior Pelvic Ring Injury With Symphysis DisruptionArmsInternal Fixator, Symphyseal Plate
NCT02403154 naterminatednot on this mapstarted 2014, after this paper: background citation

Prospective Randomized Comparison of Subcutaneous Internal Fixation and External Fixation for Anterior Pelvic Ring Fractures Requiring Stabilization

TypeinterventionalSponsorIndiana UniversityRan2014 to 2016Enrolled4ConditionsAnterior Pelvic Ring FracturesArmsInternal Fixator, External fixator
NCT02569619 phase2completednot on this mapstarted 2014, after this paper: background citation

Evaluation of an Intervention to Promote Physical Activity in Outpatients With Mental Disorders: Motivational Determinants of Adherence, Effect on Cognitive Determinants of Physical Activity, Physical Activity, Sitting Time and Clinical Symptoms

TypeinterventionalSponsorCharite University, Berlin, GermanyRan2014 to 2016Enrolled86ConditionsMental DisordersArmsActivity Intervention, Healthy Diet Intervention
NCT02699294 nacompletednot on this mapstarted 2017, after this paper: background citation

Comparison of Effectiveness of Two Different Stretching Exercises Combined With Pressure Release Technique on Latent Trigger Points in The Pectoralis Minor Muscle

TypeinterventionalSponsorIstanbul UniversityRan2017 to 2017Enrolled40ConditionsMyofascial Trigger Point PainArmsManual pressure release, Contract-relax PNF stretch, Z-stretch
NCT02761733 nacompletednot on this mapstarted 2013, after this paper: background citation

Researching the Effectiveness of a Decision-Support Tool for Adult Consumers With Mental Health Needs and Their Care Managers

TypeinterventionalSponsorFelton InstituteRan2013 to 2016Enrolled240ConditionsMental DisordersArmsMoving Patient Outcomes toward Wellness and Recovery (mPOWR)
NCT02869165 phase4completednot on this mapstarted 2017, after this paper: background citation

The Effects of Vaginal Estrogen and a Nonhormonal Alternative on the Vaginal and Urinary Microbiome in Women With Genitourinary Syndrome of Menopause: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of LouisvilleRan2017 to 2019Enrolled110ConditionsAtrophic Vaginitis, Menopause, Recurrent Urinary Tract InfectionsArmsConjugated equine estrogen topical cream, Apricot kernel oil
NCT02972879 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Effectiveness of Non-surgical Interventions for the Trigger Finger: a Randomized Clinical Trial

TypeinterventionalSponsorBeatriz Sernajoto Cristiani PedroRan2018 to 2020Enrolled132ConditionsTrigger FingerArmsTherapeutic modalities: Orthotic (Group 1), Therapeutic modalities: LLLT (Group 2), Therapeutic modalities: Paraffin (Group 3), Corticosteroid injection (Group 4)
NCT03157713 nacompletednot on this mapstarted 2017, after this paper: background citation

Financial Incentive Strategies for Weight Loss in Obese Patients Living in Socioeconomically Disadvantaged Neighborhoods

TypeinterventionalSponsorUniversity of California, Los AngelesRan2017 to 2021Enrolled668ConditionsObeseArmsGoal-Directed Financial Incentives, Enhanced Usual Care, Outcome-based Financial Incentives
NCT03158714 nacompletednot on this mapstarted 2016, after this paper: background citation

The Alabama Healthy Marriage and Relationship Education Initiative

TypeinterventionalSponsorAuburn UniversityRan2016 to 2020Enrolled1,858ConditionsHealthy Marriage, Healthy RelationshipArmsCouples Connecting Mindfully, ELEVATE
NCT03196258 naterminatednot on this mapstarted 2018, after this paper: background citation

Cognitive Behavioural Therapy to Improve Outcomes of High Risk Patients Following Internal Fixation of Extremity Fractures: A Randomized Controlled Trial (SPOC-CBT)

TypeinterventionalSponsorMcMaster UniversityRan2018 to 2019Enrolled8ConditionsPain, Postoperative, Fractures, Closed, Fractures, OpenArmsCognitive behavioural therapy
NCT03205449 nacompletednot on this mapstarted 2017, after this paper: background citation

Parenting for Lifelong Health-Philippines: Randomized Controlled Trial of a Culturally-adapted Parenting Program on Reducing the Risk of Violence Against Children in Low-income Filipino Families With Children Aged 2 to 6 Years in Manila

TypeinterventionalSponsorAteneo de Manila UniversityRan2017 to 2019Enrolled120ConditionsChild MaltreatmentArmsMasayang Pamilya Para Sa Batang Pilipino Parenting Programme (MaPa), Parenting Effectiveness Service
NCT03218982 nacompletednot on this mapstarted 2017, after this paper: background citation

A Culturally-Relevant Approach to Reducing Dementia Caregiver Stress in an Underserved Population

TypeinterventionalSponsorUniversity of California, DavisRan2017 to 2020Enrolled11ConditionsAlzheimer's Disease (Incl Subtypes), Cognitive ImpairmentArmsEnhanced psycho-education about dementia and caregiving
NCT03279198 nacompletednot on this mapstarted 2010, after this paper: background citation

Increasing Colorectal and Breast Cancer Screening in Women

TypeinterventionalSponsorIndiana UniversityRan2010 to 2017Enrolled1,196ConditionsBreast Cancer Female, Colorectal CancerArmsTIWeb, CSC, UC, TIWeb+CSC
NCT03338842 nacompletednot on this mapstarted 2018, after this paper: background citation

Virtual Reality Treatment for Phantom Limb Pain

TypeinterventionalSponsorUniversity of PennsylvaniaRan2018 to 2019Enrolled14ConditionsLower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Phantom Limb PainArmsDistractor and Lower limb VR
NCT03387436 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Treatment as Usual vs. Additional Collaborative Advance Care Planning to Improve Quality of Life for Palliative Cancer Patients: a Randomized Controlled Trial

TypeinterventionalSponsorPD. Dr. med. Carola SeifartRan2017 to 2020Enrolled280ConditionsAdvanced Cancer, Neoplasms, End Stage CancerArmsSham-Intervention, Study-Intervention
NCT03421522 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Intercostobrachial Nerve Sparing in Breast Cancer Surgery to Reduce Persistent Post-surgical Pain - an International Randomized Controlled Trial

TypeinterventionalSponsorMcMaster UniversityRan2019 to 2020Enrolled50ConditionsPost-surgical Pain, Pain, Chronic, Intercostal Pain, Breast CancerArmsICBN preservation surgery
NCT03451760 phase2unknown statusnot on this mapstarted 2018, after this paper: background citation

Feru-guard (Ferulic Acid and Angelica Archangelica Extract) for Behavioral Symptoms in Dementia

TypeinterventionalSponsorGlovia Co., Ltd.Ran2018 to 2019Enrolled70ConditionsBehavioral and Psychiatric Symptoms of DementiaArmsFeru-guard 100M, Feru-guard 100M Placebo
NCT03496090 nacompletednot on this mapstarted 2018, after this paper: background citation

Randomized Multicentric Controlled Clinical Trial of Parallel Groups to Evaluate the Non-therapeutic Inferiority of a Free Diet With a Progressive Diet, in the Treatment of Non-complicated Acute Diverticulitis

TypeinterventionalSponsorHospital General Universitario Reina Sofía de MurciaRan2018 to 2019Enrolled134ConditionsDiverticulitis, Acute Diverticulitis, Diverticulitis, Colonic, Uncomplicated Diverticular DiseaseArmsFree diet, Progressive diet
NCT03503760 nacompletednot on this mapstarted 2016, after this paper: background citation

Efficacy of Extremely Low Magnetic Field (ELF) in Fibromyalgic Patients: Effect on Symptoms Severity, Sleep and Quality of Life.

TypeinterventionalSponsorAzienda Ospedaliera Universitaria Integrata VeronaRan2016 to 2017Enrolled48ConditionsFibromyalgiaArmsLIMFA Therapy®
NCT03514095 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Cognitive Stimulation in the Elderly: Individual Intervention on Cognitive Frailty

TypeinterventionalSponsorEscola Superior de Enfermagem de CoimbraRan2017 to 2018Enrolled80ConditionsNeurocognitive Disorders, DementiaArmsIndividual Cognitive Stimulation Therapy Program
NCT03640767 naunknown statusnot on this mapstarted 2018, after this paper: background citation

The Effectiveness of Text Message-based Rehabilitation Program on Cardiometabolic Risk Factors for Patients With Peripheral Artery Disease Post-surgical Revascularization: A Randomized Controlled Trial

TypeinterventionalSponsorCaritas Institute of Higher EducationRan2018 to 2020Enrolled160ConditionsMessage-based Rehabilitation for Peripheral Artery Disease PatientsArmsMessage-based lifestyle intervention
NCT03683004 completednot on this mapstarted 2018, after this paper: background citation

Chemotherapy-Related Changes in Neurocognitive Function and Symptoms in Colorectal Cancer Patients: A Pilot Study

TypeobservationalSponsorUniversity of NebraskaRan2018 to 2020Enrolled40ConditionsColorectal Cancer
NCT03757637 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Yeur-Hur Lai, PhD, RN, School of Nursing, College of Medicine, National Taiwan University

TypeinterventionalSponsorNational Taiwan University HospitalRan2018 to 2025Enrolled380ConditionsDifferentiated Thyroid CancerArmsNLSCP, ICT supported HAP
NCT03803865 nacompletednot on this mapstarted 2019, after this paper: background citation

A Randomized Controlled Trial Comparing a 30 Day Mediation App to 30 Day Active Problem Solving App: Stress Management in Customer Service Representatives

TypeinterventionalSponsorCarnegie Mellon UniversityRan2019 to 2019Enrolled100ConditionsPsychological Stress, InflammationArmsMindfulness Training, Reflection and Problem Solving
NCT03904004 unknown statusnot on this mapstarted 2019, after this paper: background citation

Impact of Peroral Endoscopic Myotomy and Other Treatments for Oesophageal Motility Disorders on Bolus Transport and Gastro-oesophageal Reflux. The pFlow Study

Typeobservational_patient_registrySponsorFundacion Miguel ServetRan2019 to 2022Enrolled60ConditionsEsophageal Motility Disorders, Gastro-esophageal RefluxArmsPeroral endoscopic myotomy, Neumatic dilatation, Botulinum toxin injection, Laparoscopic Heller Myotomy
NCT03938974 completednot on this mapstarted 2013, after this paper: background citation

The Emergence and Evolution of Social Self-Management of Parkinson's Disease

TypeobservationalSponsorTufts UniversityRan2013 to 2019Enrolled146ConditionsParkinson Disease
NCT03949959 nacompletednot on this mapstarted 2019, after this paper: background citation

Effectiveness of Conservative Multimodal Physiotherapy in Chronic Whiplash-associated Disorders With Facet-mediated Pain Undergoing Platelet Rich Plasma (PRP) Treatment: a Series of Single Case Experimental Designs (SCEDs).

TypeinterventionalSponsorUniversity of CalgaryRan2019 to 2021Enrolled6ConditionsWhiplash Injuries, Neck Injuries, Platelet Rich PlasmaArmsMultimodal physiotherapy
NCT04062383 naterminatednot on this mapstarted 2020, after this paper: background citation

Positive Psychology for Acute Coronary Syndrome Patients: A proof-of Concept Feasibility Trial

TypeinterventionalSponsorNorthwestern UniversityRan2020 to 2020Enrolled1ConditionsACS - Acute Coronary SyndromeArmsPositive Psychology + Motivational Interviewing
NCT04186468 nacompletednot on this mapstarted 2020, after this paper: background citation

Piloting an ICU Follow-up Clinic to Improve Health Related Quality of Life After a Prolonged Intensive Care Stay

TypeinterventionalSponsorOtto-von-Guericke University MagdeburgRan2020 to 2021Enrolled40ConditionsCritical Illness, PICS, Post Intensive Care SyndromeArmsICU follow-up clinic
NCT04295954 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Effect of a Semi-Presence Yoga Program, With Virtual Tutorized Home Tracking, on Dysmenorrhea in University Students: Randomized an Controlled Clinical Trial Protocol.

TypeinterventionalSponsorUniversity of HuelvaRan2020 to 2021Enrolled50ConditionsDysmenorrhea Primary, Pain, Menstrual, YogaArmsYoga Intervention
NCT04313972 phase4terminatednot on this mapstarted 2021, after this paper: background citation

IC PaIN Trial: Interstitial Cystitis Pain Improvement With Naltrexone, the Effect of Low Dose Naltrexone on Symptoms and Pain of Patients With Interstitial Cystitis/Painful Bladder Syndrome a Randomized Placebo-controlled Prospective Trial

TypeinterventionalSponsorEndeavor HealthRan2021 to 2023Enrolled3ConditionsInterstitial Cystitis, Painful Bladder Syndrome, Bladder Pain Syndrome, Low Dose NaltrexoneArmslow-dose naltrexone, Placebo oral tablet
NCT04351789 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Impact of a Minimal Psychoeducational Intervention Versus Standard of Care on Anxiety Among Hospitalized COVID-19 Patients in Denmark: a Randomized Clinical Trial

TypeinterventionalSponsorCopenhagen University Hospital, HvidovreRan2020 to 2023Enrolled66ConditionsCOVID-19, Mental Health, Psychoeducation, AnxietyArmsPsychoeducational intervention
NCT04403659 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Monitoraggio Telematico di Pazienti Ricoverati in Ospedalizzazione a Domicilio Per Scompenso Cardiaco Acuto - Studio Pilota

TypeinterventionalSponsorA.O.U. Città della Salute e della ScienzaRan2020 to 2021Enrolled50ConditionsHeart Failure, With Decompensation, Heart Failure,Congestive, Heart Failure AcuteArmsTelemedicine/telemonitoring (TM) suite
NCT04482582 nacompletednot on this mapstarted 2021, after this paper: background citation

Early Percutaneous Cryoablation for Pain Control After Rib Fractures Among Elderly Patients

TypeinterventionalSponsorStanford UniversityRan2021 to 2025Enrolled127ConditionsRib FracturesArmsCryoneurolysis, Standard of Care
NCT04502121 nacompletednot on this mapstarted 2020, after this paper: background citation

Preoperative Optimization of Cardiac Valve Patients' Expectations - a Randomized Controlled Trial

TypeinterventionalSponsorPhilipps University MarburgRan2020 to 2023Enrolled89ConditionsCardiac Valve DiseaseArmsEXPECT: Preoperative optimization of cardiac valve patient's expectations
NCT04524767 nacompletednot on this mapstarted 2021, after this paper: background citation

Community Partnered Participatory Approach to Implement Depression Screening in Black Churches

TypeinterventionalSponsorColumbia UniversityRan2021 to 2025Enrolled505ConditionsDepressionArmsSBIRT, Referral as Usual
NCT04571502 naterminatednot on this mapstarted 2025, after this paper: background citation

Integration of Health Information Technology and Promotion of Personhood in Family-Centered Dementia Care

TypeinterventionalSponsorFlorida International UniversityRan2025 to 2025Enrolled42ConditionsNeurocognitive Disorders, Alzheimer Disease, CaregiverArmsMy PATI ( Person Assisted Touchscreen Interface)
NCT04630470 nacompletednot on this mapstarted 2019, after this paper: background citation

Effect of Massage Therapy With Lavender Oil on Severity of Restless Legs Syndrome and Quality of Life in Hemodialysis Patients: A Randomized Controlled Trial

TypeinterventionalSponsorTC Erciyes UniversityRan2019 to 2019Enrolled58ConditionsHemodialysisArmsmassage therapy with lavender oil, massage therapy with baby oil
NCT04669379 naterminatednot on this mapstarted 2021, after this paper: background citation

Preoperative Optimization of Patient's Expectations by the Use of an Online-Tool - a Randomized Controlled Trial

TypeinterventionalSponsorPhilipps University MarburgRan2021 to 2022Enrolled29ConditionsPatients Undergoing SurgeryArmsEXPECT: Preoperative optimization of patient's expectations
NCT04757961 nacompletednot on this mapstarted 2021, after this paper: background citation

Evaluation of an ACT-based Narrative Intervention for Individuals Taking Antidepressant Medication

TypeinterventionalSponsorUtah State UniversityRan2021 to 2023Enrolled90ConditionsDepressive SymptomsArmsLifeStories
NCT04879641 nacompletednot on this mapstarted 2021, after this paper: background citation

Optimizing Cognitive-behavioral Therapy for Social Anxiety Disorder Using the Factorial Design: What Works Best and How Does it Work (OPTIMIZE)

TypeinterventionalSponsorUniversity of BernRan2021 to 2024Enrolled464ConditionsSocial Anxiety Disorder (Social Phobia)ArmsExposure, Attention Training, Cognitive Restructuring, Psychoeducation
NCT04896983 unknown statusnot on this mapstarted 2021, after this paper: background citation

National Survey of Mental Health in the Second Year After COVID-19 Outbreak: Multilevel Analysis of Individual and Societal Factors

TypeobservationalSponsorUniversity of BelgradeRan2021 to 2022Enrolled1,200ConditionsMental Health Impairment
NCT04969991 phase2terminatednot on this mapstarted 2021, after this paper: background citation

A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety, Tolerability, and Efficacy of Varespladib in Patients Hospitalized With Severe COVID 19 Caused by SARS-CoV-2

TypeinterventionalSponsorOphirex, Inc.Ran2021 to 2022Enrolled18ConditionsCoronavirus Disease 2019, Disease Caused by Severe Acute Respiratory Syndrome Coronavirus 2ArmsVarespladib, Placebo
NCT04982094 nacompletednot on this mapstarted 2021, after this paper: background citation

Counting On U: Supporting SME Advisors and Owners Towards Better Mental Health

TypeinterventionalSponsorLeanne SaxonRan2021 to 2023Enrolled1,599ConditionsMental Health Wellness 1ArmsMental Health First Aid and Relationship Building Training, Mental Health First Aid
NCT05090683 nacompletednot on this mapstarted 2021, after this paper: background citation

Evaluation of a Mind-body Based Application for the Treatment of Chronic/Persistent Pain.

TypeinterventionalSponsorUniversity of the Fraser ValleyRan2021 to 2022Enrolled198ConditionsChronic Pain, Migraine, Chronic Pain SyndromeArmsMind-body mobile application
NCT05099744 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Satisfaction With Life and Quality of Life in Adults With Depressive and Anxious Symptoms: A Pilot Randomized Clinical Trial

TypeinterventionalSponsorUniversity of MinhoRan2021 to 2024Enrolled48ConditionsAnxiety, DepressionArmsElectrostimulation Therapy, Relaxation, Placebo
NCT05143671 completednot on this mapstarted 2021, after this paper: background citation

Prospective Evaluation for Hybrid Cardiac Procedures

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2021 to 2025Enrolled134ConditionsLeft Main Coronary Artery Disease, Left Anterior Descending Coronary Artery Stenosis, Valve Disease, Heart, Carotid StenosisArmsCoronary artery bypass grafting, Percutaneous coronary intervention, Surgical valve replacement, Carotid artery stenting
NCT05214937 narecruitingnot on this mapstarted 2022, after this paper: background citation

A Distance-based, Randomized Controlled Trial for Reducing Sedentary Behaviour Among Prostate Cancer Survivors

TypeinterventionalSponsorUniversity of TorontoRan2022 to 2026Enrolled120ConditionsSedentary Behavior, Cancer of ProstateArmsIntervention, FitBit Only
NCT05217004 nacompletednot on this mapstarted 2022, after this paper: background citation

Systematic Evaluation of Mobile Applications for Informal Caregivers of People Living With Dementia

TypeinterventionalSponsorUniversity of ReginaRan2022 to 2022Enrolled175ConditionsCaregiver Burden, Stress, DementiaArmsDementia Talk mobile application, CLEAR Dementia Care mobile application
NCT05267353 naunknown statusnot on this mapstarted 2013, after this paper: background citation

School of Nursing, College of Medicine, National Taiwan University

TypeinterventionalSponsorNational Taiwan University HospitalRan2013 to 2022Enrolled390ConditionsHead and Neck Squamous Cell CarcinomaArmsExercise intervention program
NCT05296265 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain: In-Person Treatment

TypeinterventionalSponsorAlbert Einstein Healthcare NetworkRan2022 to 2025Enrolled46ConditionsPhantom Limb PainArmsVR treatment for phantom limb pain
NCT05330611 nacompletednot on this mapstarted 2023, after this paper: background citation

Treatment of Adult Traumatic Rib Fractures With Percutaneous Cryoneurolysis for Pain Control (Trauma-PC2-study)

TypeinterventionalSponsorStanford UniversityRan2023 to 2026Enrolled43ConditionsRib FracturesArmsCryoneurolysis of Intercostal Nerves, Standard of Care
NCT05366712 naactive not recruitingnot on this mapstarted 2022, after this paper: background citation

Nexus Evaluation Primary Trident II UNcemented shEll (NEPTUNE): A Longitudinal Cohort Study of the Hydroxyapatite Coated Trident II Acetabular System in Total Hip Arthroplasty

TypeinterventionalSponsorNHS LothianRan2022 to 2034Enrolled125ConditionsArthritis of Hip, Hip Dysplasia, Hip Arthropathy, Hip OsteoarthritisArmsStryker Trident® II HA coated cementless acetabula component
NCT05546658 early_phase1active not recruitingnot on this mapstarted 2022, after this paper: background citation

Effects of Psilocybin in Obsessive Compulsive Disorder

TypeinterventionalSponsorJohns Hopkins UniversityRan2022 to 2027Enrolled35ConditionsObsessive-Compulsive DisorderArmsPsilocybin
NCT05571306 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Can Diabetes Distress be Reduced by Improving Entry to Care for People With Type 2 Diabetes Mellitus: A Cluster-randomized Trial

TypeinterventionalSponsorUniversity of Southern DenmarkRan2022 to 2024Enrolled512ConditionsType 2 Diabetes, Diabetes DistressArmsfour core components care
NCT05648916 unknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of Celecoxib on Heterotopic Bone Formation Following Cementless Total Hip Arthroplasty

TypeobservationalSponsorMcGill University Health Centre/Research Institute of the McGill University Health CentreRan2022 to 2023Enrolled200ConditionsHeterotopic OssificationArmsCelecoxib
NCT05676320 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

A Multicentre, Single-blind, RCT to Document the Safety and Efficacy of the Use of a Bone Cement With or Without Inossia® Cement Softener for Patients With Vertebral Compression Fractures

TypeinterventionalSponsorInossia ABRan2021 to 2026Enrolled203ConditionsVertebral Compression FractureArmsV-Flex, V-Steady
NCT05720429 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Evaluation of the Usefulness and Feasibility of a Psychoeducational Intervention to Prevent the Negative Psychological Impact of the COVID-19 Pandemic on Primary Health Care Professionals

TypeinterventionalSponsorFundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaRan2022 to 2024Enrolled2,500ConditionsMental Health Issue, Burnout, ProfessionalArmsPsychoeducational program
NCT05732935 nacompletednot on this mapstarted 2023, after this paper: background citation

Fasting to Provide Energy Needed to Help Adults in Need of Cognitive Enhancement (FASTING ENHANCE)

TypeinterventionalSponsorUniversity of FloridaRan2023 to 2026Enrolled45ConditionsOverweight and Obesity, Time Restricted Feeding, Alzheimer DiseaseArmsTime Restricted Eating intervention, Successful Aging Comparison Group (LEARN)
NCT05904249 nacompletednot on this mapstarted 2022, after this paper: background citation

Investigation of the Effectiveness of Telerehabilitation in Individuals With Rotator Cuff Tear

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2022 to 2023Enrolled44ConditionsRotator Cuff Tears, Physiotherapy and Rehabilitation, Shoulder Pain, Rotator Cuff InjuriesArmsInternet Based Synchronized Telerehabilitation, Face-to-Face Rehabilitation
NCT05987410 narecruitingnot on this mapstarted 2023, after this paper: background citation

EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in obEse or oveRweight Diabetic patiEnts With Cardiovascular Disease. The VENERE Study

TypeinterventionalSponsorFondazione Don Carlo Gnocchi ETSRan2023 to 2026Enrolled105ConditionsCardiovascular Diseases, Diabete Type 2, Overweight and ObesityArmsNordic Walking (NW), Standard Rehabilitation (SR), Cardiological Counselling (CC)
NCT06091163 nacompletednot on this mapstarted 2024, after this paper: background citation

A Randomised Controlled Trial Evaluating the Efficacy and Mechanisms of a Ketogenic Diet as an Adjunctive Treatment for People With Treatment-resistant Depression

TypeinterventionalSponsorUniversity of OxfordRan2024 to 2024Enrolled88ConditionsTreatment Resistant Depression, Depression, Mental Illness, Mental DisorderArmsKetogenic Diet, Phytonutrient Diet
NCT06295276 nacompletednot on this mapstarted 2024, after this paper: background citation

Does a Teletherapy-guided Exercise Programme Improve Pain Intensity, Disability, and Quality of Life in Nursing Students With Back and Neck Pain Compared to a Control Group?

TypeinterventionalSponsorHochschule OsnabruckRan2024 to 2024Enrolled48ConditionsLow Back Pain, Neck PainArmsteletherapy-guided exercise programme, Waiting list/control intervention/delayed teletherapy intervention
NCT06465589 nacompletednot on this mapstarted 2024, after this paper: background citation

PRIVATE - Preference Research: Investigating Variations of Anonymity, Transparency, and Efficacy in Digital Health Applications

TypeinterventionalSponsorUniversity of BernRan2024 to 2026Enrolled452ConditionsSocial AnxietyArmsJOURNeY anonymous, JOURNeY standard
NCT06599177 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Patients with COPD: Assessment of Psychosocial Status and the Impact of Psychosocial Interventions

TypeinterventionalSponsorUniversity of CreteRan2024 to 2026Enrolled160ConditionsChronic Obstructive Pulmonary Disease (COPD)ArmsInformational leaflet
NCT06754982 narecruitingnot on this mapstarted 2025, after this paper: background citation

Temporal Differences in Pain, Muscle Stiffness, and Function in Subjects With Plantar Fasciitis After Myofascial Release Therapy

TypeinterventionalSponsorUniversidad Católica del MauleRan2025 to 2027Enrolled50ConditionsPlantar Fasciitis of Both FeetArmsMyofascial release
NCT06797245 narecruitingnot on this mapstarted 2025, after this paper: background citation

The APPROVE Trial: A Randomized Controlled Trial Evaluating the Efficacy and Safety of a Prescription Digital Therapeutic for Treatment of Overactive Bladder in Women

TypeinterventionalSponsorMedstar Health Research InstituteRan2025 to 2028Enrolled596ConditionsOveractive Bladder (OAB), Urinary Urgency, Urinary Urge Incontinence (UUI), NocturiaArmsRiSolve App, AUGS Patient Handouts
NCT06942780 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Preliminary Efficacy and Feasibility Analysis of Cognitive Training, Group Social Activities, Physical Exercise, and MIND Diet in Patients With Mild Cognitive Impairment

TypeinterventionalSponsorXuanwu Hospital, BeijingRan2025 to 2025Enrolled30ConditionsMild Cognitive Impairment (MCI)ArmsExercise intervention, Social intervention, Dietary intervention, Cognitive intervention, Health Education Manual
NCT06959472 nacompletednot on this mapstarted 2025, after this paper: background citation

The Impact of Hyperarch Fascia Training on Ankle Sprain Pain and Exercise Performance in Athletic Men and Women

TypeinterventionalSponsorApplied Science & Performance InstituteRan2025 to 2025Enrolled62ConditionsAnkle Injuries, Sprains and Strains, Joint InstabilityArmsHyperarch Fascia Training
NCT07044323 narecruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment

TypeinterventionalSponsorAlbert Einstein Healthcare NetworkRan2025 to 2026Enrolled44ConditionsPhantom Pain Following Amputation of Lower Limb, AmputationArmsActive Virtual Reality Treatment
NCT07143396 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluation of a Mind-Body Application in Combination With a Graded Movement Program for the Treatment of Chronic Pain

TypeinterventionalSponsorUniversity of the Fraser ValleyRan2025 to 2025Enrolled100ConditionsChronic Pain, Migraine, Chronic Pain SyndromeArmsMind-body mobile application and guided movement
NCT07156188 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

The PAPYRUS Study: Permanent vs. Absorbable Sutures in PrimarY Repair of Umbilical HerniaS: A Multicentre, Single-blind, Non-inferiority, Randomized Controlled Trial

TypeinterventionalSponsorUniversity of British ColumbiaRan2026 to 2030Enrolled914ConditionsHernia Surgery, Umbilical Hernia RepairArmsPermanent Suture, Absorbable
NCT07268144 nacompletednot on this mapstarted 2016, after this paper: background citation

Effectiveness of a Supervised University-Based Physical Activity and Health Education Program on Lifestyle and Psychological Well-being: A Controlled Educational Intervention Study

TypeinterventionalSponsorFundacin Biomedica Galicia SurRan2016 to 2017Enrolled159ConditionsHealthy Lifestyle, Cardiovascular Risk Factors, Sedentary Behavior, Psychological Well-beingArmsPonte en Forma Program
NCT07410689 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

SAFE.AI: Developing and Testing an AI-based Hybrid Chatbot for Financial Empowerment in Rural Cancer Care

TypeinterventionalSponsorUniversity of UtahRan2026 to 2027Enrolled60ConditionsCancer, Financial ToxicityArmsRule-Based Chatbot, Hybrid Chatbot
NCT07646509 narecruitingnot on this mapstarted 2025, after this paper: background citation

An Ecological Momentary Intervention for the Reduction of Impairment in Somatic Symptom Disorder

TypeinterventionalSponsorUniversity of ViennaRan2025 to 2026Enrolled40ConditionsSomatic Symptom Disorder (DSM-5), Impairment, Psychological Factors, Persistent Physical SymptomsArmsMusic listening, Cognitive reappraisal, No intervention
NCT07752199 nacompletednot on this mapstarted 2025, after this paper: background citation

Effects of Neural Mobilization Combined With Manual Therapy on Functional Outcomes and Exploratory Infrared Thermographic Changes in Patients With Lumbar Disc Herniation: A Randomized Sham-Controlled Trial

TypeinterventionalSponsorLonghua HospitalRan2025 to 2025Enrolled72ConditionsHerniated Disc, Sciatica Due to Intervertebral Disc DisorderArmsNeural Mobilization, Sham Neural Mobilization, Manual Therapy
3 · Its place in the literature

Who cites it

7,717 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  3. Cancer patient distress and health service use is linked with carer distress: evidence from a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  5. Longitudinal impact of sodium bicarbonate therapy on health-related quality of life in pre-dialysis chronic kidney disease with metabolic acidosis: a pragmatic trial in Malaysia.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  19. Percutaneous left atrial appendage closure following catheter ablation therapy of atrial fibrillation: outcomes stratified by bleeding risk - a sub-analysis of the OPTION study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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7,657 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

J WareHealth Institute, New England Medical Center, Boston, Massachusetts, USA.
M Kosinski
S D Keller

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regression methods were used to select and score 12 items from the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) to reproduce the Physical Component Summary and Mental Component Summary scales in the general US population (n=2,333). The resulting 12-item short-form (SF-12) achieved multiple R squares of 0.911 and 0.918 in predictions of the SF-36 Physical Component Summary and SF-36 Mental Component Summary scores, respectively. Scoring algorithms from the general population used to score 12-item versions of the two components (Physical Components Summary and Mental Component Summary) achieved R squares of 0.905 with the SF-36 Physical Component Summary and 0.938 with SF-36 Mental Component Summary when cross-validated in the Medical Outcomes Study. Test-retest (2-week)correlations of 0.89 and 0.76 were observed for the 12-item Physical Component Summary and the 12-item Mental Component Summary, respectively, in the general US population (n=232). Twenty cross-sectional and longitudinal tests of empirical validity previously published for the 36-item short-form scales and summary measures were replicated for the 12-item Physical Component Summary and the 12-item Mental Component Summary, including comparisons between patient groups known to differ or to change in terms of the presence and seriousness of physical and mental conditions, acute symptoms, age and aging, self-reported 1-year changes in health, and recovery for depression. In 14 validity tests involving physical criteria, relative validity estimates for the 12-item Physical Component Summary ranged from 0.43 to 0.93 (median=0.67) in comparison with the best 36-item short-form scale. Relative validity estimates for the 12-item Mental Component Summary in 6 tests involving mental criteria ranged from 0.60 to 107 (median=0.97) in relation to the best 36-item short-form scale. Average scores for the 2 summary measures, and those for most scales in the 8-scale profile based on the 12-item short-form, closely mirrored those for the 36-item short-form, although standard errors were nearly always larger for the 12-item short-form.

Indexed as

Health StatusHealth SurveysMental HealthCross-Sectional StudiesHumansLongitudinal StudiesOutcome Assessment, Health CareRegression AnalysisReproducibility of ResultsUnited States

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 83 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.