ArticleJournal of virology1996
SFA-1, a novel cellular gene induced by human T-cell leukemia virus type 1, is a member of the transmembrane 4 superfamily.
Article in Journal of virology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 77 citations in OpenAlex.
- The controversial role of CD151 in different solid tumors: promoter or suppressor?Cancer cell international · 2025Review
- High Yield Expression of Recombinant CD151 in E. coli and a Structural Insight into Cholesterol Binding Domain.Molecular biotechnology · 2019Article
- The tetraspanin CD151 in papillomavirus infection.Viruses · 2014Review
- The tetraspanin CD151-ARSA mutant inhibits angiogenesis via the YRSL sequence.Molecular medicine reports · 2013Article
- Adeno associated viral vector-delivered and hypoxia response element-regulated CD151 expression in ischemic rat heart.Acta pharmacologica Sinica · 2011Article
- Adeno-associated viral vector mediated and cardiac-specific delivery of CD151 gene in ischemic rat hearts.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2011Article
- Activation of the ERK signaling pathway is involved in CD151-induced angiogenic effects on the formation of CD151-integrin complexes.Acta pharmacologica Sinica · 2010Article
- Tetraspanins and vascular functions.Cardiovascular research · 2009Review
- Assessment of myocardial blood perfusion improved by CD151 in a pig myocardial infarction model.Acta pharmacologica Sinica · 2009Article
- Highly enhanced expression of CD70 on human T-lymphotropic virus type 1-carrying T-cell lines and adult T-cell leukemia cells.Journal of virology · 2008Article
- Role of CD151, A tetraspanin, in porcine reproductive and respiratory syndrome virus infection.Virology journal · 2007Article
- Tetraspanins in viral infections: a fundamental role in viral biology?Journal of virology · 2005Review
- Comparative studies on cellular gene regulation by HIV-1 based vectors: implications for quality control of vector production.Gene therapy · 2005Article
- Characterization of mice lacking the tetraspanin superfamily member CD151.Molecular and cellular biology · 2004Article
- CD151 regulates epithelial cell-cell adhesion through PKC- and Cdc42-dependent actin cytoskeletal reorganization.The Journal of cell biology · 2003Article
- Clinical significance of transmembrane 4 superfamily in colon cancer.British journal of cancer · 2003Article
- An extracellular site on tetraspanin CD151 determines alpha 3 and alpha 6 integrin-dependent cellular morphology.The Journal of cell biology · 2002Article
- The tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomes.The Journal of cell biology · 2000Article
- Transmembrane 4 superfamily protein CD151 (PETA-3) associates with beta 1 and alpha IIb beta 3 integrins in haemopoietic cell lines and modulates cell-cell adhesion.The Biochemical journal · 1999Article
- Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration.Molecular biology of the cell · 1998Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel cellular gene termed SFA-1 was isolated by differential hybridization of a cDNA library, using probes obtained from an adult T-cell leukemia cell line in comparison with probes obtained from normal CD4+ T cells and the MOLT-4 cell line. The mRNA of the SFA-1 gene is approximately 1.6 kb in size and encodes a protein of 253 amino acids, containing four putative transmembrane domains, a number of cysteine residues, and one potential N-glycosylation site in a major hydrophilic region between the third and fourth transmembrane domains. Expression of the SFA-1 gene was either absent or present at a low level in lymphoid cells but was up-regulated after transformation by human T-cell leukemia virus type 1 and transactivated by Tax. SFA-1 was broadly expressed in many human cell types and conserved in different species. Computer-aided comparison showed that SFA-1 had significant sequence homology and common structural features with members of the transmembrane 4 superfamily. SFA-1 antigen was detected as a 29-kDa membrane protein by immunoblotting, using anti-SFA-1 monoclonal antibody.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.