ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience1996
Glutamate responses of bipolar cells in a slice preparation of the rat retina.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 206 citations in OpenAlex.
- Divergent molecular and circuit mechanisms underlie light entrainment of retinal and suprachiasmatic nucleus circadian clocks.Cellular and molecular life sciences : CMLS · 2026Article
- A sign-inverted receptive field of inhibitory interneurons provides a pathway for ON-OFF interactions in the retina.Nature communications · 2023Article
- Involvement of transient receptor potential channels in ocular diseases: a narrative review.Annals of translational medicine · 2022Article
- Digital reconstruction and quantitative morphometric analysis of bipolar cells in live rat retinal slices.The Journal of comparative neurology · 2022Article
- The temporal structure of the inner retina at a single glance.Scientific reports · 2020Article
- Differential expression of PKCα and -β in the zebrafish retina.Histochemistry and cell biology · 2019Article
- Different Activity Patterns in Retinal Ganglion Cells of TRPM1 and mGluR6 Knockout Mice.BioMed research international · 2018Article
- Cone signals in monostratified and bistratified amacrine cells of adult zebrafish retina.The Journal of comparative neurology · 2017Article
- Article
- Electrophysiological fingerprints of OFF bipolar cells in rat retina.Scientific reports · 2016Article
- ON-OFF Interactions in the Retina: Role of Glycine and GABA.Current neuropharmacology · 2014Article
- Intersublaminar vascular plexus: the correlation of retinal blood vessels with functional sublaminae of the inner plexiform layer.Investigative ophthalmology & visual science · 2014Article
- Nitric oxide modulates the temporal properties of the glutamate response in type 4 OFF bipolar cells.PloS one · 2014Article
- Bipolar cell-photoreceptor connectivity in the zebrafish (Danio rerio) retina.The Journal of comparative neurology · 2012Article
- Organizational motifs for ground squirrel cone bipolar cells.The Journal of comparative neurology · 2012Article
- Characterization of Trpm1 desensitization in ON bipolar cells and its role in downstream signalling.The Journal of physiology · 2012Article
- Development and degeneration of cone bipolar cells are independent of cone photoreceptors in a mouse model of retinitis pigmentosa.PloS one · 2012Article
- Faster thalamocortical processing for dark than light visual targets.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- A novel type of complex ganglion cell in rabbit retina.The Journal of comparative neurology · 2011Article
- A positive feedback synapse from retinal horizontal cells to cone photoreceptors.PLoS biology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whole-cell currents from >70 voltage-clamped bipolar cells were recorded in a slice preparation of the rat retina. The recorded cells were identified and classified by intracellular staining with Lucifer yellow. Glutamate, the specific agonists (+/-)-2-amino-4-phosphonobutyric acid (AP-4) and kainate (KA), and the antagonist 6-cyanoquinoxaline-2,3-dione (CNQX) were applied. The cells could be isolated from presynaptic influences by the co-application of bicuculline, strychnine, and cobalt ions. Responses to AP-4 were elicited only from bipolar cells with axons stratifying in the inner part of the inner plexiform layer (IPL). AP-4 caused an outward current in these cells attributable to the closure of nonspecific cation channels. Responses to kainate representing a direct action of the drug on the recorded cells were observed only in bipolar cells with axons stratifying in the outer part of the IPL. KA caused a CNQX-sensitive inward current in these cells, associated with openings of nonspecific cation channels. The results predict that cone bipolar (CB) cells with axons terminating in the outer IPL are OFF-bipolars, whereas those with axons terminating in the inner IPL are ON-bipolars. Most of the cells expressed GABA-gated Cl- conductances. In rod bipolar and in some CB cells, only part of the GABA-induced currents could be blocked by the application of bicuculline, suggesting the presence of GABAc receptors in addition to GABAA receptors.
Indexed as
Identifiers
8622124PMC6579066W2114972922What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.