Evidence map›Paper›PMID 8617890›Full record

ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology1996

Blood vessel adaptation to gravity in a semi-arboreal snake.

D J Conklin, H B Lillywhite, K R Olson, R E Ballard, A R Hargens

Abstract read
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In one paragraph

Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Autonomic control of heart rate during orthostasis and the importance of orthostatic-tachycardia in the snake Python molurus.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2014
    Article
  5. Cardiovascular responses of semi-arboreal snakes to chronic, intermittent hypergravity.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 1996
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

D J ConklinLife Sciences Division, NASA-Ames Research Center, Moffett Field, CA 94035-1000, USA.
H B Lillywhite
K R Olson
R E Ballard
A R Hargens
Ames Research Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of vasoactive agonists on systemic blood vessels were examined with respect to anatomical location and gravity acclimation in the semi-arboreal snake, Elaphe Obsoleta. Major blood vessels were reactive to putative neurotransmitters, hormones or local factors in vessel specific patterns. Catecholamines, adenosine triphosphate, histamine and high potassium (80 mM) stimulated significantly greater tension per unit vessel mass in posterior than anterior arteries. Anterior vessels were significantly more sensitive to catecholamines than midbody and posterior vessels. Angiotensin II stimulated significantly greater tension in carotid artery than in midbody and posterior dorsal aorta. Arginine vasotocin strongly contracted the left and right aortic arches and anterior dorsal aorta. Veins were strongly contracted by catecholamines, high potassium and angiotensin II, but less so by adenosine triphosphate, arginine vasotocin and histamine. Precontracted vessel were relaxed by acetylcholine and sodium nitroprusside, but not by atrial natriuretic peptide or bradykinin. Chronic exposure of snakes to intermittent hypergravity stress ( + 1.5 Gz at tail) did not affect the majority of vessel responses. These data demonstrate that in vitro tension correlates with that catecholamines, as well as other agonists, are important in mediating vascular responses to gravitational stresses in snakes.

Indexed as

Adaptation, PhysiologicalGravitationAdenosine TriphosphateAnalysis of VarianceAngiotensin IIAnimalsArteriesCatecholaminesFemaleHistamineHormonesMaleNeurotransmitter AgentsPotassiumSnakesVasotocinAdenosine TriphosphateAngiotensin IICatecholaminesHistamineHormonesNeurotransmitter AgentsPotassiumVasotocinNASA Center ARCNASA Discipline CardiopulmonaryNASA Discipline Number 14-10NASA Program Space Physiology and Countermeasures

Identifiers

PMID8617890
OpenAlexW2031742165

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.