ReviewThe Biochemical journal1996
Peptide models for membrane channels.
Review in The Biochemical journal, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 103 citations in OpenAlex.
- Novel formulations for antimicrobial peptides.International journal of molecular sciences · 2014Review
- Assembling an ion channel: ORF 3a from SARS-CoV.Biopolymers · 2013Article
- Mitochondria-mediated cardioprotection by trimetazidine in rabbit heart failure.Journal of molecular and cellular cardiology · 2013Article
- Direct visualization of the alamethicin pore formed in a planar phospholipid matrix.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Inorganic polyphosphate is a potent activator of the mitochondrial permeability transition pore in cardiac myocytes.The Journal of general physiology · 2012Article
- Observing a model ion channel gating action in model cell membranes in real time in situ: membrane potential change induced alamethicin orientation change.Journal of the American Chemical Society · 2012Article
- Peptide model helices in lipid membranes: insertion, positioning, and lipid response on aggregation studied by X-ray scattering.European biophysics journal : EBJ · 2011Article
- Oncolytic activities of host defense peptides.International journal of molecular sciences · 2011Review
- Interactions of alamethicin with model cell membranes investigated using sum frequency generation vibrational spectroscopy in real time in situ.The journal of physical chemistry. B · 2010Article
- Electron spin resonance in membrane research: protein-lipid interactions from challenging beginnings to state of the art.European biophysics journal : EBJ · 2010Review
- Molecular modeling of the reductase domain to elucidate the reaction mechanism of reduction of peptidyl thioester into its corresponding alcohol in non-ribosomal peptide synthetases.BMC structural biology · 2010Article
- Composite S-layer lipid structures.Journal of structural biology · 2009Review
- Characteristics and function of cardiac mitochondrial nitric oxide synthase.The Journal of physiology · 2009Article
- Intramembrane water associated with TOAC spin-labeled alamethicin: electron spin-echo envelope modulation by D2O.Biophysical journal · 2009Article
- Backbone dynamics of alamethicin bound to lipid membranes: spin-echo electron paramagnetic resonance of TOAC-spin labels.Biophysical journal · 2008Article
- Structure of magainin and alamethicin in model membranes studied by x-ray reflectivity.Biophysical journal · 2006Article
- Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes.Biophysical journal · 2006Article
- Conformation of peptides in lipid membranes studied by x-ray grazing incidence scattering.Biophysical journal · 2004Article
- Spontaneous changes in mitochondrial membrane potential in single isolated brain mitochondria.Biophysical journal · 2003Article
- NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating.Biophysical journal · 2002Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peptides may be synthesized with sequences corresponding to putative transmembrane domains and/or pore-lining regions that are deduced from the primary structures of ion channel proteins. These can then be incorporated into lipid bilayer membranes for structural and functional studies. In addition to the ability to invoke ion channel activity, critical issues are the secondary structures adopted and the mode of assembly of these short transmembrane peptides in the reconstituted systems. The present review concentrates on results obtained with peptides from ligand-gated and voltage-gated ion channels, as well as proton-conducting channels. These are considered within the context of current molecular models and the limited data available on the structure of native ion channels and natural channel-forming peptides.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.