ArticleBritish journal of cancer1996
Multiplicity of fibronectin-binding alpha V integrin receptors in colorectal cancer.
Article in British journal of cancer, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- Review
- The RGD motif is involved in CD97/ADGRE5-promoted cell adhesion and viability of HT1080 cells.Scientific reports · 2019Article
- Severity of local inflammation does not impact development of fibrosis in mouse models of intestinal fibrosis.Scientific reports · 2018Article
- Integrins as Therapeutic Targets: Successes and Cancers.Cancers · 2017Review
- [(18)F]FPRGD2 PET/CT imaging of integrin αvβ3 levels in patients with locally advanced rectal carcinoma.European journal of nuclear medicine and molecular imaging · 2016Article
- Pathophysiology of fistula formation in Crohn's disease.World journal of gastrointestinal pathophysiology · 2014Review
- O-Mannosylation and human disease.Cellular and molecular life sciences : CMLS · 2013Review
- Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells.Molecular & cellular proteomics : MCP · 2011Article
- Integrin alpha v beta 6 mediates the potential for colon cancer cells to colonize in and metastasize to the liver.Cancer science · 2008Article
- Is there a genetic signature for liver metastasis in colorectal cancer?World journal of gastroenterology · 2007Review
- P-selectin activates integrin-mediated colon carcinoma cell adhesion to fibronectin.Experimental cell research · 2006Article
- Integrin alpha(v)beta6-associated ERK2 mediates MMP-9 secretion in colon cancer cells.British journal of cancer · 2002Article
- Article
- Expression of alpha(v)beta6 integrin in oral leukoplakia.British journal of cancer · 2000Article
- Expression of alphav integrins and vitronectin receptor identity in breast cancer cells.British journal of cancer · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current data from in vitro and in vivo animal models indicate that fibronectin-binding integrin receptors expressed by colon cancer cells may regulate tumour growth. While individual members of the beta 1 subfamily of integrins have now been clearly identified in colorectal cancer, little information exists with respect to the alpha V subfamily. In the present study we show that alpha V can associate with multiple and different beta subunits capable of binding fibronectin in this tumour type. This is likely to have functional implications for growth and spread of colorectal cancer.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.