ArticleThe Biochemical journal1996
Structural studies on a lipoarabinogalactan of Crithidia fasciculata.
Article in The Biochemical journal, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 29 citations in OpenAlex.
- Use of Crithidia fasciculata extract for the facile enzymatic synthesis of GDP-L-[3H]Fucose.Glycobiology · 2025Article
- The lipidome ofFrontiers in cellular and infection microbiology · 2022Article
- Proteins involved in the biosynthesis of lipophosphoglycan in Leishmania: a comparative genomic and evolutionary analysis.Parasites & vectors · 2020Article
- Genetic metabolic complementation establishes a requirement for GDP-fucose inThe Journal of biological chemistry · 2017Article
- Article
- Structure of a complex phosphoglycan epitope from gp72 of Trypanosoma cruzi.The Journal of biological chemistry · 2013Article
- Biosynthesis of the fungal cell wall polysaccharide galactomannan requires intraluminal GDP-mannose.The Journal of biological chemistry · 2012Article
- Galactosaminogalactan, a new immunosuppressive polysaccharide of Aspergillus fumigatus.PLoS pathogens · 2011Article
- Sugar nucleotide pools of Trypanosoma brucei, Trypanosoma cruzi, and Leishmania major.Eukaryotic cell · 2007Article
- Secretory pathway of trypanosomatid parasites.Microbiology and molecular biology reviews : MMBR · 2002Review
- Isolation and characterization of glycosylphosphatidylinositol-anchored, mucin-like surface glycoproteins from bloodstream forms of the freshwater-fish parasite Trypanosoma carassii.The Biochemical journal · 2000Article
- Glycoinositol phospholipids from Endotrypanum species express epitopes in common with saccharide side chains of the lipophosphoglycan from Leishmania major.The Biochemical journal · 1998Article
- The surface glycoconjugates of trypanosomatid parasites.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1997Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The monosaccharide D-arabinopyranose has only been found in glycoconjugates of the trypanasomatid parasites Leishmania major, Endotrypanum schaudinni and Crithidia fasciculata. The donor molecule for the relevant arabinosyltransferases is known to be GDP-alpha-D-Arap in L. major and C. fasciculata, and the latter organism is being used to study the biosynthesis of GDP-alpha-D-Arap. In this study, we describe the structure of the terminal product of arabinose metabolism in C. fasciculata, namely lipoarabinogalactan. This molecule was purified by hydrophobic-interaction chromatography and studied by a variety of techniques, including gas chromatography-mass spectrometry, electrospray mass spectrometry and chemical and enzymic digestions. These data show that lipoarabinogalactan contains a previously described D-arabino-D-galactan polysaccharide component covalently attached to a glycosylphosphatidylinositol type of membrane anchor that is similar to, but not identical with, that found in the lipophosphoglycans of the Leishmania.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.