ArticleJapanese journal of cancer research : Gann1996
Cloning of mouse DAN cDNA and its down-regulation in transformed cells.
Article in Japanese journal of cancer research : Gann, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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2 citing papers in PubMed, 20 citations in OpenAlex.
- Neural induction and early patterning in vertebrates.Wiley interdisciplinary reviews. Developmental biology · 2013Review
- Purification and partial amino acid sequence of proteins from human epidermal keratinocyte conditioned medium.Journal of protein chemistry · 2001Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
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Abstract
Recently, we have demonstrated that DAN gene product exhibits a tumor-suppressive activity in vitro. We report here the cloning and sequencing of a mouse DAN cDNA that contains the entire coding region. Sequence analysis revealed that mouse DAM cDNA is 1691 nucleotides in length and contains an open reading frame of 178 amino acids. The deduced mouse DAN protein sequence shows 96% and 93% identity with the counterparts isolated from rat 3Y1 fibroblasts and normal human lung, respectively. Genomic Southern blot hybridization indicated that DAN gene exists as a single copy in the mouse genome. The expression of DAN gene was suppressed in a variety of transformed NIH3T3 cells when compared with that in the parental NIH3T3 cells.
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