ArticleExperientia1996
A simple, sensitive, non-stimulated photon counting system for detection of superoxide anion in whole blood.
Article in Experientia, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04177420 (Investigation for Health Efficacy of Infrared-C Radiation on Diabetes Patients in Senior's Activity Center), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation for Health Efficacy of Infrared-C Radiation on Diabetes Patients in Senior's Activity Center
Who cites it
16 citing papers in PubMed, 70 citations in OpenAlex.
- Article
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- Cardiovascular complications are resolved by tuna protein hydrolysate supplementation in rats fed with a high-fat diet.Scientific reports · 2023Article
- Nobiletin resolves left ventricular and renal changes in 2K-1C hypertensive rats.Scientific reports · 2022Article
- Diosmetin Ameliorates Vascular Dysfunction and Remodeling by Modulation of Nrf2/HO-1 and p-JNK/p-NF-κB Expression in Hypertensive Rats.Antioxidants (Basel, Switzerland) · 2021Article
- Galangin Resolves Cardiometabolic Disorders through Modulation of AdipoR1, COX-2, and NF-κB Expression in Rats Fed a High-Fat Diet.Antioxidants (Basel, Switzerland) · 2021Article
- Genistein Prevents Nitric Oxide Deficiency-Induced Cardiac Dysfunction and Remodeling in Rats.Antioxidants (Basel, Switzerland) · 2021Article
- Novel application of amino-acid buffered solution for neuroprotection against ischemia/reperfusion injury.PloS one · 2019Article
- Hesperidin Prevents Nitric Oxide Deficiency-Induced Cardiovascular Remodeling in Rats via Suppressing TGF-β1 and MMPs Protein Expression.Nutrients · 2018Article
- Composition of phenolic compounds and antioxidant attributes of Cyclea gracillima Diels extracts.Journal of food and drug analysis · 2018Article
- Article
- Synthesis and physicochemical properties of novel lophine derivatives as chemiluminescent in vitro activators for detection of free radicals.European biophysics journal : EBJ · 2015Article
- Ellagic Acid Prevents L-NAME-Induced Hypertension via Restoration of eNOS and p47phox Expression in Rats.Nutrients · 2015Article
- Association of blood arsenic levels with increased reactive oxidants and decreased antioxidant capacity in a human population of northeastern Taiwan.Environmental health perspectives · 2001Article
- The oxidative metabolism of circulating phagocytes in ankylosing spondylitis: determination by whole blood chemiluminescence.Annals of the rheumatic diseases · 2000Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A simple, sensitive, non-stimulated assay was developed to measure the superoxide anion concentration in whole blood, using an ultra-sensitive chemiluminescence (CL) analyzer and lucigenin amplification. The assay system can be performed without leukocyte isolation or stimulant administration. The blood CL levels of healthy males (362.8 +/- 337.7 counts /10 sec) were not different from those of females (335 +/- 308.7 counts/10 sec) (p=0.64), whereas the CL levels in whole blood in patients with acute pancreatitis (2522 +/- 2014 counts/10 sec) were significantly higher than those of healthy controls (p<0.001). This assay system may be valuable in the future for quantitative measurement of reactive oxygen species in various disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.