Evidence map›Paper›PMID 8606121›Full record

ArticleInfection and immunity1996

Construction and preliminary characterization of three hemagglutinin mutants of Porphyromonas gingivalis.

G Lépine, R P Ellen, A Progulske-Fox

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

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  16. Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis.Microbiology and molecular biology reviews : MMBR · 1998
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

G LépineDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, Florida 32610, USA.
R P Ellen
A Progulske-Fox
University of Florida · US

Funding

SURFACE ANTIGENS OF ORAL BACTEROIDES SPECIESR01DE007496 · NIDCR · UNIVERSITY OF FLORIDA · PI PROGULSKE-FOX, ANN · 1991 to 2005
$1.4M
SURFACE ANTIGENS OF ORAL BACTEROIDS SPECIESK04DE000336 · NIDCR · UNIVERSITY OF FLORIDA · PI PROGULSKE-FOX, ANN · 1992 to 1995
–
SURFACE ANTIGENS OF ORAL BACTEROIDES GINGIVALISR23DE007496 · NIDCR · UNIVERSITY OF FLORIDA · PI PROGULSKE-FOX, ANN · 1986 to 1986
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SURFACE ANTIGENS OF ORAL BACTEROIDES GINGIVALISR29DE007496 · NIDCR · UNIVERSITY OF FLORIDA · PI PROGULSKE-FOX, ANN · 1987 to 1990
–
NIDCR NIH HHS DE00336NIDCR NIH HHS DE07496
6 · The paper itself

Abstract

Targeted insertional mutagenesis was used to construct hagA, hagB, and hagC hemagglutinin mutants of Porphyromonas gingivalis. pJRD215-derived plasmids containing tetA(Q)2 and portions of the targeted genes were conjugated into P. gingivalis. Interruption of the three loci was confirmed by Southern hybridization, sequencing, reverse transcription-PCR, and microtiter hemagglutination assays. No significant differences in hydrophobicity or coadherence to Actinomyces viscosus were detected between the mutants and the wild-type strain.

Indexed as

Base SequenceBlotting, SouthernHemagglutinationHemagglutininsMolecular Sequence DataMutagenesis, InsertionalPolymerase Chain ReactionPorphyromonas gingivalisRNAHemagglutininsRNA

Identifiers

PMID8606121
PMCPMC173946
OpenAlexW1931391884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.