ArticleInfection and immunity1996
Binding of human fibronectin to Aspergillus fumigatus conidia.
Article in Infection and immunity, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 87 citations in OpenAlex.
- Fibronectin recognition by the emerging multidrug-resistant opportunistic fungal pathogen Candida haemulonii.Folia microbiologica · 2025Article
- Impact of Copper(II) and Silver(I) Complexes Containing 1,10-phenanthroline-5,6-dione on Cellular and Virulence Aspects ofCurrent topics in medicinal chemistry · 2025Article
- Fibronectin-binding molecules of Scedosporium apiospermum: focus on adhesive events.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Review
- Aspergillus fumigatus biofilms: Toward understanding how growth as a multicellular network increases antifungal resistance and disease progression.PLoS pathogens · 2021Review
- Review
- Interactions of Aspergillus fumigatus Conidia with Airway Epithelial Cells: A Critical Review.Frontiers in microbiology · 2016Review
- Identification of fibrinogen-binding proteins of Aspergillus fumigatus using proteomic approach.Mycopathologia · 2012Article
- Phage display against corneal epithelial cells produced bioactive peptides that inhibit Aspergillus adhesion to the corneas.PloS one · 2012Article
- Molecular mechanism of Aspergillus fumigatus adherence to host constituents.Current opinion in microbiology · 2011Review
- Paracoccidioides brasiliensis enolase is a surface protein that binds plasminogen and mediates interaction of yeast forms with host cells.Infection and immunity · 2010Article
- Melanin is an essential component for the integrity of the cell wall of Aspergillus fumigatus conidia.BMC microbiology · 2009Article
- Purification and partial characterization of a Paracoccidioides brasiliensis protein with capacity to bind to extracellular matrix proteins.Infection and immunity · 2005Article
- Rhizopus oryzae adheres to, is phagocytosed by, and damages endothelial cells in vitro.Infection and immunity · 2005Article
- Purification and partial characterization of a 32-kilodalton sialic acid-specific lectin from Aspergillus fumigatus.Infection and immunity · 2002Article
- Uptake of Aspergillus fumigatus Conidia by phagocytic and nonphagocytic cells in vitro: quantitation using strains expressing green fluorescent protein.Infection and immunity · 2002Article
- Sialylglycoconjugates and sialyltransferase activity in the fungus Cryptococcus neoformans.Glycoconjugate journal · 2002Article
- Involvement of fungal cell wall components in adhesion of Sporothrix schenckii to human fibronectin.Infection and immunity · 2001Article
- Adhesion of Aspergillus species to extracellular matrix proteins: evidence for involvement of negatively charged carbohydrates on the conidial surface.Infection and immunity · 2000Article
- Recognition of fibronectin by Penicillium marneffei conidia via a sialic acid-dependent process and its relationship to the interaction between conidia and laminin.Infection and immunity · 1999Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aspergillus fumigatus conidia exhibited the ability to bind purified human fibronectin, whereas mycelial forms did not bind the ligand, as detected by an indirect immunofluorescence assay with an antifibronectin polyclonal antibody after incubation of the cells with fibronectin. Flow cytometry confirmed that binding of the ligand to conidia was dose dependent and saturable. Pretreatment of the cells with trypsin markedly reduced binding, which suggested a protein nature for the binding sites present at the surface of conidia. Intact conidia were also able to adhere to fibronectin or antifibronectin antibodies, a significant reduction (from 88 to 92%) in the binding of conidia was noticed, thus suggesting that adhesion to the immobilized ligand was specific. Analysis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western immunoblotting with fibronectin and antifibronectin antibody of whole conidial homogenates and 2-mercaptoethanol extracts from isolated conidial cell walls allowed identification, among the complex array of protein and glycoprotein species present in both cell-free preparations, of two polypeptides with apparent molecular masses of 23 and 30 kDa which specifically interact with fibronectin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.