ArticleBritish journal of cancer1996
Allelic imbalance in the region of the BRCA1 gene in ductal carcinoma in situ of the breast.
Article in British journal of cancer, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 13 citations in OpenAlex.
- Genetic alterations on chromosome 16 and 17 are important features of ductal carcinoma in situ of the breast and are associated with histologic type.British journal of cancer · 1999Article
- Article
- Genetically abnormal clones in histologically normal breast tissue.The American journal of pathology · 1998Article
- Loss of heterozygosity at chromosome 9p in ductal carcinoma in situ and invasive carcinoma of the breast.British journal of cancer · 1998Article
- Mutation of the TP53 gene and allelic imbalance at chromosome 17p13 in ductal carcinoma in situ.British journal of cancer · 1996Article
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thirty-four cases of ductal carcinoma in situ (DCIS) of the breast, with or without associated benign or invasive disease, were analysed for allelic imbalance (AI) in the region of the BRCA1 gene. AI on 17q12-23 in DCIS was demonstrated in 74% of cases, and in the majority of cases the region of AI included the BRCA1 gene. However, two cases showed AI distal to BRCA1, supporting the presence of a second tumour-suppressor gene on 17q.
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